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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

A pre-GLP study was conducted using an internal company test protocol to measure the inhibition of respiration of wastewater microorganisms exposed to the test substance.

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
750 mg/L

Additional information

A radiorespirometric method was used to determine the compatibility of the test substance with secondary waste treatment microorganisms. The procedure used microorganisms from a domestic waste water treatment plant. These microorganisms were exposed to [14C]glucose and the test substance. The extent of conversion of the [14 C]glucose to [14C]carbon dioxide in the presence of the test substance was compared to glucose conversion in the absence of the test substance. Nominal concentrations of the test substance at 0. 75, 7.5, 75, and 750 mg/L had no observed inhibitory effects on the microorganisms over the course of a 5 hour exposure. The 5 -hour IC50 was determined to be > 750 mg/L and the NOEC was≥ 750 mg/L.