Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.022 mg/L
Assessment factor:
1 000
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
0.22 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.002 mg/L
Assessment factor:
10 000
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
75 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
0.191 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.019 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.025 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Additional information

Aquatic toxicity data is available for fish, daphnia, and aquatic algae. The most sensitive endpoints were observed with the aqautic algal study. The 72 -hour EC50 for growth rate from the algal study is being utilized to determine the PNECs for freshwater, marine water, and intermitent releases using the approriate assessment factors. The PNEC STP is calculated from the NOEC determined in a wastewater treatment microorganism respiration inhibition study using the appropriate assessmsnt factor. The equilibrium partitioning method has been utilized to calculate the PNECs for soil and sediment. The assessment of secondary poisoning is most relevant for certain lipophilic organic materials and some metal compounds. CHDA is a readily biodegradable substance with a low potential for bioaccumulation, based on a logKow value of <3.0. Thus, an assessment of secondary poisoning and the calculation of a PNECoral value for CHDA were not performed.

Conclusion on classification

CHDA is a readily biodegradable substance with a log Pow < 3.0. The lowest acute toxicity value with regards to classification is the 72 -hour ErC50 of 22 mg/L from the aquatic algal study. Chronic data is available from the algal study as the ErC10 or ErC20, 15 and 16 mg/L respectively. Based upon this substance being readlily biodegradable with a log Pow < 3.0, and with the most sensitive acute and chronic values stated above, the substance is not classified for environmental effects under the EU DSD or CLP regulations.

Under the UN GHS clasification system, the substance is classified as Acute Category 3 based upon the algal ErC50 being > 10 but 100 mg/L.