Registration Dossier
Registration Dossier
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EC number: 208-793-7 | CAS number: 541-85-5
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Acute toxicity of the read across substance (CASNr: 106-68-3) to aquatic invertebrates (Daphnia magna) was tested in a 24 h study period. EC50 after 24 h was 517 mg/l and EC0 was 175mg/L. LC50 for 5-methylheptan-3-one (CASNr: 541-85-5) after 48 h was estimated to be 44.7 mg/l using Ecosar.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 517 mg/L
Additional information
The 24 hour EC50 of 173 substances was determined by means of a standardized procedure using 24-h-old
animals from a clone of Daphnia magna. EC50 (24 h) of the read across substance (CASNr: 106-68-3) was 517 mg/l and EC0 (24 h) was 175 mg/l. The LC50 for 5-methylheptan-3-one (CASNr: 541-85-5) after 48 h was estimated to be 44.7 mg/l using Ecosar. The measured value is used for chemical safety assessment. Both values are higher or in the range of the lowest measured EC50 or LC50 value for algae and fish.
Since all effect concentrations were above 1 mg/l and 5-methylheptan-3-one (CASNr: 541-85-5) is readily biodegradable, no classification is necessary due to toxicity to daphnia.
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