Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-103-0 | CAS number: 103-34-4
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
The partition coefficient of 4,4'-Dithiodimorpholine (DTDM) was evaluated in a study performed in accordance with OECD testing guideline 117 and GLP requirements. The partition coefficient of DTDM was of 2.67 at 22°C and pH = 7.7.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 2.67
- at the temperature of:
- 22 °C
Additional information
Octanol-Water partition coefficient of DTDM was estimated at 310 (+/- 150) during a study (Michael and Gledhil, 1978) performed according to a protocol similar to OECD 107 (shake flask method). Concerning pH and Temperature, no information is clearly given in the document, consequently we consider that the estimation is done for relevant natural environmental conditions (pH = 5 – 9 and temperature = 20°C). However no sufficient information is given in the report in order to assess concerning the validity of those experimental results.
So, the partition coefficient of DTDM was also assessed in a study (Gancet, 2010) performed in accordance with OECD testing guideline 117 and GLP requirements. The partition coefficient of DTDM was of 2.67 at 22°C and pH = 7.7. Validity criteria were fulfilled.
These values indicate that DTDM is characterized by a low potential of bioaccumulation and adsorption.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
