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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Description of key information

The bioconcentration factor for the substance was estimated by QSAR to be 492 L/kg.

Key value for chemical safety assessment

BCF (aquatic species):
492 L/kg ww

Additional information

Due to technical feasability issues an experimental value could not be determined for DimerFA PEPA PAA. Analytical methods of sufficient accuracy for testing concentrations of the substance in test media and biological material were not available. Further to this it is likely that a standard OECD 305 test would not be suitable for such a strongly sorbing substance.

A QSAR was conducted using BCFBAFv3.01 in order to calculate the bioconcentration factor from an estimated log Kow. The bioconcentration factor was estimated for both linear and cyclic forms of the representative substance.

The BCF was estimated to be 492 L/kg for the linear form and 70.8 L/kg for the cyclic form. This indicates that the bioaccumulation potential for this substance will be of a low to medium level. It is likely that the large molecular size will likely limit uptake of the substance by biological membranes. As such, this substance is not considered to be bioaccumulative.

For risk assessment purposes the larger value of 492 L/kg has been taken to provide a worst case scenario.