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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Guideline-Study, without GLP-Certification, but well documented.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1994

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method C.1 (Acute Toxicity for Fish)
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
5-amino-3-(morpholin-4-yl)-1,2,3-oxadiazolidin-3-ium chloride
EC Number:
605-254-1
Cas Number:
16142-27-1
Molecular formula:
C6 H11 N4 O2 . Cl
IUPAC Name:
5-amino-3-(morpholin-4-yl)-1,2,3-oxadiazolidin-3-ium chloride

Test organisms

Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h

Test conditions

Hardness:
c(Ca2+ und Mg2+) = 2.51 mmol
Test temperature:
19.5-20.8°C
pH:
6.7-7.8
Dissolved oxygen:
7.9-8.6 mg/l
Nominal and measured concentrations:
Nominal (mg/l) % Nominal Beginn %Nominal End

Group 1: 13 36 0

Group 4: 44 56 3

Group 6: 100 74 30

Results and discussion

Effect concentrationsopen allclose all
Duration:
96 h
Dose descriptor:
LC0
Effect conc.:
27 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 27 - < 44 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC100
Effect conc.:
44 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)

Applicant's summary and conclusion

Validity criteria fulfilled:
yes