Registration Dossier
Registration Dossier
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EC number: 800-362-7 | CAS number: 1307863-78-0
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No long-term effects were observed during the chronic daphnia test. For adult mortality a 21d-EC10 of 1.35 mg/L was observed in an OECD guideline 211 test in natural river water with Daphnia magna under GLP (reliability 1) read-across from N-[(9Z)-octadec-9-en-1-yl]propane-1,3-diaminium di[(9Z)-octadec-9-enoate] (CAS no. 34140-91-5).
Key value for chemical safety assessment
Additional information
The Daphnia magna Reproduction Test (semi-static, 21 d) read-across from N-[(9Z)-octadec-9-en-1-yl]propane-1,3-diaminium di[(9Z)-octadec-9-enoate] was conducted according to OECD 211 under GLP. Nominal concentrations of N-[(9Z)-octadec-9-en-1-yl]propane-1,3-diaminiumdi[(9Z)-octadec-9-enoate] were: 0.500 - 1.00 - 2.00 - 4.00 - 8.00 mg/L. The time weighted mean measured concentrations were: 0.438 – 0.896 – 1.74 – 3.50 – 6.78 mg/L. The test item induced biologically significant adult mortality of 100 % in the concentration levels of 2.00 to 8.00 mg/L after 21 days.
An EC10- or EC50-value for the reduction of the reproductive output could not be estimated, because no reduction of the reproductive output > 10 % was observed within the tested concentration levels with surviving daphnids of 0.500 and 1.00 mg/L. The 21d-EC10 and EC50 for adult mortality (the most sensitive endpoint) were found to be 1.35 and 1.4 mg/L respectively, based on nominal concentrations.
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