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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
other: RTECS
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: 4b: Secondary source

Data source

Reference
Reference Type:
secondary source
Title:
The pharmacologic activity of alpha-(4-piperidyl)-benzhydrol hydrochloride (azacyclonol hydrochloride); an ataractive agent.
Author:
Braun DL
Year:
1956
Bibliographic source:
Journal of Pharmacology and Experimental Therapeutics. Vol. 118, Pg. 153

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
α,α-diphenylpiperidine-4-methanol hydrochloride
EC Number:
217-284-9
EC Name:
α,α-diphenylpiperidine-4-methanol hydrochloride
Cas Number:
1798-50-1
Molecular formula:
C18H21NO.ClH
IUPAC Name:
diphenyl(piperidin-4-yl)methanol hydrochloride

Test animals

Species:
mouse

Administration / exposure

Route of administration:
intraperitoneal

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
220 mg/kg bw

Applicant's summary and conclusion

Conclusions:
The substance has a LD50=220 mg/kg bw by intraperitoneal route.