Registration Dossier
Registration Dossier
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EC number: 939-523-2 | CAS number: 1471312-55-6
Endpoint summary
Administrative data
Description of key information
Additional information
The assessment is based on the data currently available. New studies, based on the category review and the final decisions issued for some of the category substances, which are also relevant for this assessment, are currently being conducted. The hazard assessment with respect to aquatic toxicity will be updated once all ongoing studies have been finalised.
The alkyl ether sulfates grouped within the AES category show similar structural, physico-chemical, environmental and toxicological properties. The approach of grouping different AES for the evaluation of their effects on human health and the environment was also made by the Danish EPA [1] and HERA [2], supporting the read across approach between structurally related AES.
The aquatic toxicity of the alkyl ether sulfates has been evaluated in studies on fish, invertebrates and algae as well as microorganisms. In most of the given studies AES were tested as sodium salts. As the cation counterpart of the AES anions is not expected to influence the ecotoxicological profile of the substance, read-across is possible between all comparable mixtures independent from the cation (e. g. sodium, magnesium, ammonium, MIPA; for details see category justification). Based on the available experimental data it is assumed that with increasing chain lengths also the toxicity increases. Therefore, using experimental data of AES with chain length >= C12 as a read-across for AES (C8-10, 1-2.5EO) Na it is considered as a worst case scenario.
The assessment of the acute and chronic toxicity is covered by a read-across to Alcohols, C8-10, ethoxylated, sulfates, ammonium salts. The EC50 (48 h) determined for Daphnia magna is > 110 mg a.i./L (nominal). Based on reproduction an NOEC of 5.3 mg a.i./L for Daphnia magna was determined in the long-term aquatic invertebrates test. For algae a NOEC value of 31.3 mg a. i /L was found and the corresponding EC50 value was assumed to be > 100 mg a.i./L. The LC50 value reported in the read-across study to fish was >120 mg a.i./L (nominal).
[1] Danish EPA - Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products (2001). Environmental Project No. 615, pp. 24-28
[2] HERA - Human & Environmental Risk Assessment on ingredients of European household cleaning products (2004). Alcohol Ethoxysulphates (AES).
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