Registration Dossier
Registration Dossier
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EC number: 210-521-7 | CAS number: 617-62-9
Endpoint summary
Administrative data
Description of key information
Additional information
Abiotic degradation:
The hydrolysis study was waived in accordance with column 2 of REACH Annex VIII, as it is not needed for readily biodegradable substances as 2-methyglutaric acid.
Biotic degradation:
An experimental study, scored as Klimisch 1, was selected as a key study. It was performed in compliance with GLP according to OECD 301D test guideline. During this test, 63.9 % biodegradation (based on O2 consumption) were reached and the 10-day window criterion was fulfilled; meaning that 2-methylglutaric acid is readily biodegradable. On this basis, no further investigation of biotic degradation is needed.
Bioaccumulation:
The bioaccumulation study was waived in accordance with column 2 of REACH Annex IX, as it is not needed for substances with low n-octanol/water partition coefficient as 2-methyglutaric acid (log Kow < - 1.3 at pH = 7).
Adsorption/desorption:
Due to the requirements of another regulation than REACH (Chinese notification), an experimental study was conducted. It was scored as Klimisch 1 and was selected as a key study. It was performed in compliance with GLP according to OECD 106 test guideline applying the batch equilibrium method to five soils. The mean Koc determined for 2-methylglutaric acid in these five soils is 2837; corresponding to a mean log Koc of 3.15.
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