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EC number: - | CAS number: 85338-42-7
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
48h EC50 (Daphnia magna, immobilization) > 100 mg/L (nominal concentration)
Key value for chemical safety assessment
Additional information
Since no reliable short term invertebrate testing is available for C8-10AS Na (CAS 85338-42-7), in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 a read-across to another structurally related category members was conducted. The short-term effects of CAS 85338-42-7 to invertebrates are assessed based on read-across data from C8AS Na (CAS 142-31-4) and C10AS Na (CAS 142-87-0).
Two 24-hour tests with Daphnia magna are available for C10AS Na (CAS 142-87-0). The first non-GLP study was performed following an AFNOR T.90301 (1974) method (Lundahl and Cabridenc 1978). The obtained results showed that the 24-hour EC50 value was 800 mg/L (nominal concentrations). Analytical measurements are not available. The other non-GLP study with Daphnia magna followed a method described by Norme Francaise Homologue, 1983, NF T90-31 (Sanchez Leal 1991). The 24-hour EC50 value was 470 mg/L. Analytical check of the test concentrations was not provided. Although no 48-hour toxicity test with C10AS Na (CAS 142-87-0) is available for aquatic invertebrates, a chronic study exists (see Section 6.1.4.). It is expected that the 48-hour EC50 value for aquatic invertebrates will be above 100 mg/L. Since the ecotoxic effects within the alkyl sulfates category are dependent on the carbon chain length, the studies with C10AS Na (CAS 142-87-0) are considered as the worst case scenario and therefore key studies for C8-10AS Na(CAS 85338-42-7).
Moreover, four reliable studies are available for C8AS Na (CAS 142-31-4). The key, GLP short term toxicity test with Daphnia magna was performed according to OECD 202 guideline (Neven 1993). Daphnids were exposed in the semi-static conditions to five test concentrations up to 100 mg/L (nominal concentrations in agreement with the measured ones). Based on mobility of daphnids, the 48-hour EC50 value was determined to be above 100 mg/L (nominal concentration). Moreover, three supporting 24-hour tests with Daphnia magna are available for C8AS Na (CAS 142-31-4). The non-GLP study of Richterich (2001) was performed according to OECD 202 guideline with Daphnia magna. Daphnids were exposed in the static test to fourteen different test concentrations up to the nominal concentration of 1000 mg/L. Analytical measurements are not available. The 24-hour EC50 value based on mobility was above 240 mg/L (nominal concentration). Lundahl (1978) reports a non-GLP test with Daphnia magna which was performed according to AFNOR T.90301 (1974) method. The result showed that the 24-hour EC50 value was 4350 mg/L. No analytical measurements were given. The last supporting study followed a method described by "Norme Francaise Homologue, 1983, NF T90-31" (Sanchez Leal 1991). The 24-hour test with Daphnia magna resulted in the EC50 value above 900 mg/L (nominal concentration, analytical measurements are not provided).
Due to structural and property similarities with the tested category members the above results are also applicable to C8-10AS Na(CAS 85338-42-7). The reliable 48-hour EC50 value of C8-10AS Na (CAS 85338-42-7) to aquatic invertebrates is expected to be above 100 mg/L.
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