Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
1.025 mg/L
Assessment factor:
100
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
1.025 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.102 mg/L
Assessment factor:
1 000
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
10.05 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
106.499 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
106.499 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
30.413 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Classification is not triggered based on available data, according to REGULATION (EC) No 1272/2008 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006.

Conclusion on classification

Classification of 5-nitrovanillin for effects in the environment

In determining the classification appropriate to 5-nitrovanillin, it is necessary to consider all available evidence concerning its persistence, potential to accumulate and predicted or observed environmental fate and behaviour that may present a long-term and/or delayed danger to the structure and/or functioning of aquatic ecosystems. These points are considered below. 

 

Persistence

Reliable studies are available to demonstrate that 5-nitrovanillin is non persistent in the aquatic environment as it is considered to have rapid biodegradation in the water. However, it is persistent in the soil and sediment compartment. Thus, it can be inferred that 5-nitrovanillin is persistent in character.  

 

5-nitrovanillin is therefore classified as a persistent (P) chemical. 

 

Potential to accumulate

The measured log Kow values for 5-nitrovanillin is less than 4 (Log Kow = 0.301). The potential for 5-nitrovanillin to bioaccumulate in the tissues of organisms; that inhabit aquatic or terrestrial matrices is negligible as the BCF factor for the substance is less than 1000.  

 

 The calculated BCF of 5-nitrovanillin is 4.2 dimensionless and below the threshold of 2000. 

 

5-nitrovanillin does not satisfy the criterion for classification as bioaccumulative (B).

 

The toxicity values of fish, invertebrates and algae are LC50 =114.9535mg/L, LC50 =131.7071mg/L are EC50 =102.496mg/L, respectively. Thus, based upon these values, it is considered that 5-nitrovanillin shall not exhibit aquatic toxicity within the dose levels mentioned in the three aquatic trophic levels 

 

So,5-nitrovanillin does not satisfy the environmental effects criterion for classification as aquatic toxic chemical (T).

 

Thus it can be inferred that 5-nitrovanillin is Persistent (P) but not a bio-accumulative and toxic chemical and so as per Annex XIII of the REACH regulation the substance is not considered as a PBT chemical.