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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

- Growth rate inhibition 
EC50 (72h) = 5.93 mg/L
EC10 (72h) = 4.24 mg/L
NOEC (72h) = 1.16 mg/L
LOEC (72h) = 3.97 mg/L
- Inhibition of yield
EC50 (72h) = 4.98 mg/L
EC10 (72h) = 3.32 mg/L
NOEC (72h) = 1.16 mg/L
LOEC (72h) = 3.97 mg/L

Key value for chemical safety assessment

EC50/LC50 for freshwater algae:
5.93 mg/L
EC10, LC10 or NOEC for freshwater algae:
4.24 mg/L

Additional information

The toxicity test to aquatic algae (key_toxicity to aquatic algae_2013_ReL2) performed according to OECD 201 (2011) and GLP was rated with RL=2 (reliable with restrictions) and used as key study. The influence of the test item on the growth of the freshwater green algae Pseudokirchneriella subcapitata was assessed in a static dose response test.

The results indicate that the test item inhibits the growth of the freshwater green alga Pseudokirchneriella subcapitata after 72 hours with the following effect values:

The 72-hour EC50 (Yield) was calculated to be 4.98 mg test item/L and the 72-hour EC50 (Growth rate) value was calculated to be 5.93 mg test item/L.

The 72-hour EC10 (Yield) was calculated to be 3.32 mg test item/L and the 72-hour EC10 (Growth rate) value was calculated to be 4.24 mg test item/L.

The 72-hour NOEC (Yield) was determined to be 1.16 mg test item/L and the associated 72-hour LOEC (Yield) was 3.97 mg test item/L.

The 72-hour NOEC (Growth rate) was determined to be 1.16 mg test item/L and the associated 72-hour LOEC (Growth rate) was 3.97 mg test item/L.

All results refer to mean measured concentrations at t = 0h as most of the tested concentrations were below the limit of detection at the end of the test.