Registration Dossier
Registration Dossier
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EC number: 609-962-1 | CAS number: 41851-59-6
Endpoint summary
Administrative data
Description of key information
Rac-1-(3-Methoxyphenyl)ethylamine (read across, CAS 62409-13-6) showed a corrosive potential to the skin (OECD 431) and to the eyes (HET-CAM Test).
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
Skin corrosion
Based on the results it was concluded, that rac-1-(3-Methoxyphenyl)ethylamine (read across, CAS 62409-13-6) shows a corrosive potential in the EpiDerm skin corrosivity test. The test method does not yet allow for the differentiation of severity of the effect. The results however indicate moderate corrosivity. For final assignment of a risk phrase at present, further evidence or results from an in vivo study would be needed. [BASF, 2007]
Eye irritation
Based on the results it was concluded, that rac-1-(3-Methoxyphenyl)ethylamine
(read across, CAS 62409-13-6)
caused serious eye damage in the HET-CAM Test under the test conditions. [BASF, 2007]Effects on skin irritation/corrosion: corrosive
Effects on eye irritation: corrosive
Justification for classification or non-classification
Based on the available data for rac-1-(3-Methoxyphenyl)ethylamine (read across, CAS 62409-13-6) (S)-1-(4-Methoxyphenyl)ethylamine is subject to C&L:
according to Regulation 1272/2008/EC: eye/skin corrosion, H314
according to Directive 67/548/EEC: corrosive: R34
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