Registration Dossier

Administrative data

Endpoint:
repeated dose toxicity: dermal
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:

Data source

Materials and methods

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion

Conclusions:
Effects upon repeated skin contact with the substance were not investigated. This is not required as the substance was non-toxic in an acute dermal toxicity study (see 5.2.1.3), repeat-dose toxicity was assessed by oral route and the physicochemical properties (see discussion under 5.1.1) are not in favour of a significant dermal absorption.
Executive summary:

Effects upon repeated skin contact with the substance were not investigated. This is not required as the substance was non-toxic in an acute dermal toxicity study (see 5.2.1.3), repeat-dose toxicity was assessed by oral route and the physicochemical properties (see discussion under 5.1.1) are not in favour of a significant dermal absorption.