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Administrative data

Endpoint:
dissociation constant
Type of information:
other: Measurement of individual dissociation constants of the UVCB substance is not possible
Remarks:
the UVCB substance is insoluble in water
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008

Materials and methods

Test guideline
Guideline:
OECD Guideline 112 (Dissociation Constants in Water)
Principles of method if other than guideline:
The column elution method was chosen for the determination of the hydrosolubility.Deviation : The first step of preliminary test was done at 23°C and not at 20°C
- The sand was washed only one time with acetone instead of two times These deviations were not considerated to have affected the quality or the interpretation of the result.

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Dissociating properties:
not determined
Remarks:
The hydrosolubility of LCE07100 is equal or lower than 1mg/L
Dissosciation constant
Remarks on result:
not determinable
Remarks:
The hydrosolubility of LCE07100 is equal or lower than 1mg/L. the substance is an UVCB containing several ionisable components so measurement of individual dissociation constants using the complete UVCB is not possible. Furthermore, the substance is insoluble in water. Therefore this measurement is scientifically not possible: the test does not need to be proposed.

Applicant's summary and conclusion

Conclusions:
Considering REACH Annex IX 7.16 criteria, the dissociation constant should be determined. However the substance is an UVCB containing several ionisable components so measurement of individual dissociation constants using the complete UVCB is not possible. Furthermore, the substance is insoluble in water. Therefore this measurement is scientifically not possible: the test does not need to be proposed.
Executive summary:

Considering REACH Annex IX 7.16 criteria, the dissociation constant should be determined. However the substance is an UVCB containing several ionisable components so measurement of individual dissociation constants using the complete UVCB is not possible. Furthermore, the substance is insoluble in water. Therefore this measurement is scientifically not possible: the test does not need to be proposed.