Registration Dossier

Physical & Chemical properties

Stability in organic solvents and identity of relevant degradation products

Some information in this page has been claimed confidential.

Administrative data

Endpoint:
stability in organic solvents and identity of relevant degradation products
Type of information:
other: there is no need to make the aforementioned test performed
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
2004

Materials and methods

Test guideline
Guideline:
other: According to the composition of this UVCB, to the literature and to the SEPPIC’s knowledge, the substance “Acetalization products between glucose and C20/22 alcohol” could be reasonably considered as stable in a wide range of organic solvents.

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: waxy pearl
Details on test material:
Identification:
Acetalization product between glucose and C20/22(even numbered)-alcohol
Batch: T30715
Purity: 100% commercial product
Dry Matter: 99.89%
Retest Date: 11 February 2016
Storage Conditions: At room temperature at 20 ± 5 °C, in the dark.

Results and discussion

Test substance stable:
yes
Transformation products:
no

Any other information on results incl. tables

Considering REACH Annex IX 7.15 criteria, the stability in organic solvents and the identity of relevant degradation products should be assessed. According to the composition of this UVCB, to the literature and to the SEPPIC’s knowledge, the substance “Acetalization products between glucose and C16/18 alcohol” could be reasonably considered as stable in a wide range of organic solvents. By stable, we mean no chemical degradation of any of components of the substance. The substance is perfectly stable in aprotic solvent such as dimethylformamide, dimethylsulfoxide, ether, alkane and organochloride. In solvents such alcohols, a reaction could theoretically occur at high temperature ( > 110°C) with an acidic catalyst which could lead to a modification of the composition of the substance by forming short chain corresponding alkyl glucosides. However, in standard condition, neither degradation nor modifications were observed. To the best of our knowledge, there is no experimental account about any degradation of the substance in any solvents. That is why we thought there is no need to make the aforementioned test performed. This test does not need to be proposed.

Applicant's summary and conclusion

Conclusions:
Considering REACH Annex IX 7.15 criteria, the stability in organic solvents and the identity of relevant degradation products should be assessed. According to the composition of this UVCB, to the literature and to the SEPPIC’s knowledge, the substance “Acetalization products between glucose and C20/22 alcohol” could be reasonably considered as stable in a wide range of organic solvents. By stable, we mean no chemical degradation of any of components of the substance. The substance is perfectly stable in aprotic solvent such as dimethylformamide, dimethylsulfoxide, ether, alkane and organochloride. In solvents such alcohols, a reaction could theoretically occur at high temperature ( > 110°C) with an acidic catalyst which could lead to a modification of the composition of the substance by forming short chain corresponding alkyl glucosides. However, in standard condition, neither degradation nor modifications were observed. To the best of our knowledge, there is no experimental account about any degradation of the substance in any solvents. That is why we thought there is no need to make the aforementioned test performed. This test does not need to be proposed.
Executive summary:

Considering REACH Annex IX 7.15 criteria, the stability in organic solvents and the identity of relevant degradation products should be assessed. According to the composition of this UVCB, to the literature and to the SEPPIC’s knowledge, the substance “Acetalization products between glucose and C20/22 alcohol” could be reasonably considered as stable in a wide range of organic solvents. By stable, we mean no chemical degradation of any of components of the substance. The substance is perfectly stable in aprotic solvent such as dimethylformamide, dimethylsulfoxide, ether, alkane and organochloride. In solvents such alcohols, a reaction could theoretically occur at high temperature ( > 110°C) with an acidic catalyst which could lead to a modification of the composition of the substance by forming short chain corresponding alkyl glucosides. However, in standard condition, neither degradation nor modifications were observed. To the best of our knowledge, there is no experimental account about any degradation of the substance in any solvents. That is why we thought there is no need to make the aforementioned test performed. This test does not need to be proposed.