Registration Dossier

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: ECOSAR (a module of EPISuite) is a validated QSAR tool
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other: Body Responsible for test
Title:
Unnamed
Report Date:
1991

Materials and methods

Test guideline
Guideline:
other: REACH guidance on QSARs

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Smiles code: CN(C)C(Cc1ccccc1)(CC)C(=O)c2ccc(cc2)N3CCOCC3

Results and discussion

Effect concentrations
Duration:
96 h
Dose descriptor:
EC50
Effect conc.:
< 1 mg/L
Remarks on result:
other: QSAR estimation

Applicant's summary and conclusion

Validity criteria fulfilled:
not applicable
Conclusions:
It is assumed that the substance, or the products of photolysis, as very toxic to aquatic organisms
Executive summary:

It is assumed that the substance, or the products of photolysis, is very toxic to aquatic organisms based on the result to fish and aquatic invertebrates. Modelling with ECOSAR (part of EPISuite) confirms the high expected toxicity.

The study is not possible to perform and was not conducted as part of the original notification.