Registration Dossier
Registration Dossier
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EC number: 200-493-4 | CAS number: 60-93-5
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
In this case report, patients were tested with a patch test. The patch tests using quinine dihydrochloride in aqueous solution were initially positive at 1 %, 0.1 % and 0.01 %, but on retesting have become negative. In result photo patch test were positive at 1% and 0.1 % quinine dihydrochloride.
Migrated from Short description of key information:
Photo patch test were positive at 1% and 0.1 % quinine dihydrochloride. Quinine dihydrochloride is obviously a contact allergen.
Justification for selection of skin sensitisation endpoint:
Endpoint selection: 7.10.4
Skin sensitisation was shown in a human case report.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Quinine dihydrochloride is obviously a contact allergen. Based on the results quinine dihydrochloride has to be classified category 1A.
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