Registration Dossier

Administrative data

Endpoint:
distribution modelling
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Value is predicted from model. Thus, it provides an approximation compared to experimental measure.

Data source

Reference
Reference Type:
other: unpublished calculation
Title:
Unnamed
Year:
2013
Report Date:
2013

Materials and methods

Model:
calculation according to Mackay, Level III
Calculation programme:
EPI Suite v4.11
Release year:
2 013
Media:
other: air- water- soil- sediment

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
not specified
Details on test material:
Calculation is based on the structure and / or properties of quinine dihydrochloride.

Results and discussion

Percent distribution in media

Air (%):
0
Water (%):
8.85
Soil (%):
76.8
Sediment (%):
14.3

Any other information on results incl. tables

   air  water  soil  sediment

mass amount (%)

4.09E-008  8.85  76.8  14.3
half-life (hr) 1.46 900  1.8E+003  8.1E+003
emissions (kg/hr)  1000  1000  1000  0
fugacity (atm)   1.36E-026 3.71E-028  5.47E-029  4.58E-028

reaction (kg/hr)

 1.24E-003   437  1.9E+003 78.6

advection (kg/hr)

2.62E-005 568  0  18.4

reaction (%)

 4.14E-005  14.6  63.3  2.62

advection (%)

8.74E-007  18.9  0  0.613

persistence time: 2.14E+003 hr

reaction time: 2.66E+003 hr

advection time: 1.09E+003 hr

percent reacted: 80.5

percent advected: 19.5

half-lives (hr), (based upon Biowin and Aopwin):

air: 1.464

water: 900

soil: 1800

sediment: 8100

biowin estimate: 2.423 (weeks-months)

advection time:

air: 100

water: 1000

sediment: 5E+004

Applicant's summary and conclusion

Conclusions:
According to the calculated distribution quinine dihydrochloride mainly retains to soil.
Executive summary:

According to the fugacity model, Level III, the distribution of quinine dihydrochloride to air - water - soil - sediment is 0.0000000409 - 8.85 - 76.8 - 14.3 %. These results show, that the majority retains in soil, while there is low amount available in the air, water and sediments.