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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: This study was selected as the key study because the information provided for the hazard endpoint is sufficient for the purpose of classification and labelling and/or risk assessment.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report date:
2013

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling point/boiling range)
Deviations:
no
Remarks:
The study was conducted according to the test guidelines in effect at the time of study conduct.
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
Deviations:
no
Remarks:
The study was conducted according to the test guidelines in effect at the time of study conduct.
GLP compliance:
yes
Type of method:
method according to Siwoloboff

Test material

Constituent 1
Chemical structure
Reference substance name:
2-amino-3-hydroxy-N'-[(E)-(2,3,4-trihydroxyphenyl)methylidene]propanehydrazide hydrochloride
EC Number:
940-411-0
Cas Number:
1353749-74-2
Molecular formula:
C10H14ClN3O5
IUPAC Name:
2-amino-3-hydroxy-N'-[(E)-(2,3,4-trihydroxyphenyl)methylidene]propanehydrazide hydrochloride
Details on test material:
- Purity: 99.97%

Results and discussion

Boiling point
Decomposition:
yes
Decomp. temp.:
>= 220 - <= 221 °C
Remarks on result:
other: The test substance melted/foamed between 220 and 221°C, leaving a black powdery residue. No boiling point/range was observed.

Any other information on results incl. tables

Typically, when a test material melts, a boiling point capillary is inserted below the liquid depth of the melted test substance. At no point during the testing was this possible with this compound. As the temperature increased, the solid test substance began to undergo significant colour changes. The original white to off-white colour of the test material changed as a function of temperature. The test substance became darker in colour with increasing temperature. At 220.5°C, a phase change appeared to take place. The test substance appeared to melt and foam. The now black test substance rose up the sides of the boiling point tube. The original depth of the test material inside each sample tube was approximately 8 mm. After the testing, the black, solid powdery residue height inside each tube was approximately 23 mm. Even if a boiling point capillary could have been inserted inside the boiling point tube (during this phase transition), the sample colour would have prevented any observance of sample bubbling. At a temperature of 250°C, the testing for each sample was discontinued. These colour changes are an indication of thermal degradation. The test substance did not provide a boiling point/range for any of the three tests.

Applicant's summary and conclusion

Conclusions:
This study and the conclusions which are drawn from it fulfil the quality criteria (validity, reliability, repeatability).
The test substance thermally degraded as the instrument block temperature approached 220°C. No boiling point/range was observed.
Executive summary:

The boiling point was determined using a modification of the Siwoloboff procedure described in OECD 103. Subsamples of the test substance were heated (in boiling point tubes and capillaries) using a temperature-controlled metal heating block instead of a liquid bath.

As the test substance was heated it appeared to melt and foam, then become a black, solid, powdery residue. The test substance thermally degraded as the instrument block temperature approached 220°C. No boiling point/range was observed.