Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 12 Jan 2021 - 24 Dec 2021
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: Method A2 of ASTM international E 1148 – 02
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: turbidity method
- Key result
- Water solubility:
- 0 g/L
- Conc. based on:
- test mat.
- Incubation duration:
- 24 h
- Temp.:
- 20 °C
- pH:
- 6.8
- Executive summary:
A method based on Method A2 of ASTM International E 1148 – 02 guideline was applied for the determination of the water solubility of MDEA-Esterquat C18 unsatd. The samples at the lowest target concentration (i.e., 0.01 mg/L) were analyzed using the validated UPLC-MS/MS method.
The water solubility of the test material at 20°C was 8.47 x 10-6 g/L. The pH of the aqueous sample was 6.8.
Reference
The results of the test on the determination of the turbidity for the test samples are given in the table below. It was decided to correct for the mean turbidity of the blank samples. Samples at a test material concentration of ≥644 mg/L were omitted from the curve because using them resulted in a negative water solubility.
In the concentration range of 0.00982 to 227 mg/L, a linear relationship between response and test material concentration was observed. The equation of the regression line was:
Y = 0.0900 x A – 0.640 (r = 0.993, n = 16), where Y is the turbidity measured in NTU and A
is the nominal concentration of the test material.
Since the slope and fit of the curve changes at low concentration levels, the water solubility was not calculated with the equation of the curve. The sample with “zero turbidity” was analyzed with the validated UPLC-MS/MS method.
Turbidity of Test Material Solutions
Nominal concentration [mg/L] | Turbidity [NTU] | Corrected turbidity 1 [NTU] |
644 | 59.2 | 59.1 |
644 | 59.6 | 59.5 |
227 | 14.2 | 14.1 |
227 | 14.3 | 14.2 |
28.4 | 1.77 | 1.68 |
28.4 | 1.66 | 1.57 |
9.82 | 1.08 | 0.986 |
9.82 | 1.07 | 0.976 |
0.982 | 0.515 | 0.421 |
0.982 | 0.533 | 0.439 |
0.196 | 0.315 | 0.221 |
0.196 | 0.304 | 0.210 |
0.0393 | 0.202 | 0.108 |
0.0393 | 0.199 | 0.105 |
0.00982 | 0.101 | 0.00650 |
0.00982 | 0.104 | 0.00950 |
0 | 0.093 | n.a. |
0 | 0.096 | n.a. |
1 Corrected for the mean turbidity of the blank samples.
n.a. Not applicable.
Water Solubility of the Test Material
Target concentration [g/L] | Analyzed concentration [g/L] | Mean [g/L] | pH |
10 x 10-6 10 x 10-6 | 8.34 x 10-6 8.60 x 10-6 | 8.47 x 10-6 | 6.8 6.8 |
Description of key information
8.47E-06 g/L at 20°C, pH 6.8 (Method A2 of ASTM International E 1148 – 02)
Key value for chemical safety assessment
- Water solubility:
- 0 g/L
- at the temperature of:
- 20 °C
Additional information
A method based on Method A2 of ASTM International E 1148 – 02 guideline was applied for the determination of the water solubility of MDEA-Esterquat C18 unsatd. The samples at the lowest target concentration (i.e., 0.01 mg/L) were analyzed using the validated UPLC-MS/MS method.
The water solubility of the test material at 20°C was 8.47E-06 g/L. The pH of the aqueous sample was 6.8.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.