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Diss Factsheets

Physical & Chemical properties

Density

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Administrative data

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Reference
Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
11 May 2018 to 06 November 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.3 (Relative Density)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
air comparison pycnometer (for solids)
Specific details on test material used for the study:
Batch number: TG 3774
Purity: 97% (by HPLC)
Expiry date: 01 July 2020
Key result
Type:
relative density
Density:
1.16 other: dimensionless
Temp.:
20 °C

Calibration

The pressure readings and the calculated volume for the reference and sample cells are shown in the following table:

Determination

P1 (psig)

P2 (psig)

P3 (psig)

P4 (psig)

Reference cell volume (mL)

Sample cell volume (mL)

1

17.256

6.533

17.296

8.570

90.762

148.973

2

17.283

6.545

17.246

8.544

90.909

149.149

3

17.082

6.470

17.218

8.529

91.015

149.281

Mean reference cell volume: 90.895 mL

Mean sample cell volume: 149.135 mL

As the reference cell and sample cell volume were within the defined tolerance: 90.953 ± 1.0 mL and 149.225 ± 1.0 mL for the reference and sample cell, respectively. The gas comparison pycnometer was therefore considered acceptable for use.

Sample

The pressure readings, calculated volumes and density values obtained for the test item are shown in the following table:

Determination

Replicate

P1(sample) (psig)

P2(sample) (psig)

Volume (mL)

Density (g/L)

Mean Density (g/L)

1

A

17.153

7.782

39.679

1.18E3

1.16E3

B

17.255

7.860

40.488

1.15E3

C

17.130

7.813

40.742

1.15E3

2

A

17.170

7.754

38.757

1.17E3

1.15E3

B

17.194

7.805

39.792

1.14E3

C

17.242

7.832

39.926

1.14E3

  Duplicate determinations were performed until a reproducibility of <20 g/L was obtained.

Conclusions:
The relative density of the substance was measured to be 1.16, in a GLP study performed using method EC A.3 and OECD 2019. The density was 1.16 g/mL at 20.0 ± 0.5 °C.
Executive summary:

The relative density of the substance was measured to be 1.16, in a GLP study performed using method EC A.3 and OECD 2019. The density was 1.16 g/mL at 20.0 ± 0.5 °C.

Description of key information

The density of the test item has been determined to be 1.16 g/mL at 20.0 ± 0.5 °C, and a relative density of 1.16.

Key value for chemical safety assessment

Relative density at 20C:
1.16

Additional information