Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- September 12-29, 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
Test material
- Test material form:
- solid: particulate/powder
- Details on test material:
- Batch No.: UGe-RS Kilo 1
Color: Yellow
Odor: Not specific
Storage conditions: room temperature
Solubility and stability: Very good solubility in water, stable in solution at least 2 days
Expiring date: 12.12.2018
Correction factor: 1.07
Constituent 1
- Specific details on test material used for the study:
- Test Item name: Yellow LF 6911
Batch No. UGe-RS Kilo 1
Purity 93.3 % (organic part excluding water and salts not containing similar chromophore)
Expiry date 12 December 2018
Storage room temperature
Results and discussion
Water solubility
- Key result
- Water solubility:
- 380.2 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 125 g/L
- Incubation duration:
- 24 - 72 h
- Temp.:
- 20 °C
- pH:
- 6.9 - 7.7
Any other information on results incl. tables
Results of the determination of water solubility of Yellow LF 6911
Sampling time |
Measured concentrationoftest item,g/L |
Measured pH |
|
Test vessels |
Mean |
||
After 24h |
355.6 |
361.1 |
6.9 |
381.7 |
6.9 |
||
345.9 |
6.9 |
||
After 48h |
361.5 |
390.3 |
7.0 |
407.0 |
7.0 |
||
402.5 |
7.1 |
||
After 72h |
395.6 |
389.1 |
7.1 |
404.8 |
7.1 |
||
367.0 |
7.1 |
||
Mean with confidence interval (95 %) |
380.2 ± 17.95 |
- |
|
RSD % |
6 |
- |
|
Applicant's summary and conclusion
- Conclusions:
- In conclusion the water solubility of Yellow LF 6911 was determined to be 380.2 ± 17.95 g/L (95% confidence interval) at 20 °C ± 1 °C using the flask method for the performance of the main test
- Executive summary:
The purpose of the study was to evaluate the solubility of test item in water at 20 ± 0.5 °C. The test item is dissolved in water at a temperature somewhat above the test temperature. When saturation is achieved the mixture is cooled and kept at the test temperature, stirring as long as necessary to reach equilibrium. Subsequently, the mass concentration of the substance in the aqueous solution, which must not contain any undissolved particles, is determined by a suitable analytical method.
The water solubility of Yellow LF 6911 was determined to be 380.2 ± 17.95 g/L (95% confidence interval) at 20 °C ± 0.5 °C using the flask method for the performance of the main test
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