Registration Dossier
Registration Dossier
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EC number: 941-788-4 | CAS number: -
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Calcination product of titanium dioxide, tin monoxide, zinc oxide and dihydrogen wolframate
- EC Number:
- 941-788-4
- Molecular formula:
- Ti 1 Sn 0,6 Zn 0,5 W 0,15 O 4
- IUPAC Name:
- Calcination product of titanium dioxide, tin monoxide, zinc oxide and dihydrogen wolframate
- Details on test material:
- - Physical state: solid, red
- Analytical purity: > 99 %
- Storage condition of test material: room temperature
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- Analysis of the test media samples for Sn was conducted on fresh media at 0 hours and on
corresponding old media at 96 hours. Measured test concentrations were determined
from samples of control and test solution.
Test solutions
- Vehicle:
- no
- Details on test solutions:
- Due to the fact that the test substance is inorganic with a very low water solubility a WAF was prepared. The test substance was added into 6 L test water and stirred for 24 hours. Then, undissolved test substance was allowed to settle for about one hour. Dispersion was taken from the middle of the vessel and filtered at 0.45 µm.
Test organisms
- Test organisms (species):
- other: Chinese Rare Minnow (Gobiocypris rarus)
- Details on test organisms:
- Fish were bred in the lab.
Fish were acclimatized to the test conditions for more than 14 days prior the test.
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 96 h
Test conditions
- Hardness:
- Total hardness as CaCO3 (mg/L): 125
- Test temperature:
- 21.9-22.3 °C
- pH:
- 7.33-7.72
- Dissolved oxygen:
- 78-93%
- Nominal and measured concentrations:
- measured concentrations remained
within ± 20 % Sn of the start concentration (geometric mean of 5.12 µg Sn/L)
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- EL50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat. (total fraction)
- Basis for effect:
- mortality (fish)
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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