Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: - | CAS number: -
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The key value was derived from a study performed under GLP conditions and according to OECD 203. No mortalities were observed throughout the study resulting in an LC50 for Rainbow trout (Oncorhynchus mykiss) of > 49 mg a.i./L after an exposure of 96 hours in a semi-static test in freshwater.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 49 mg/L
Additional information
The acute fish study of Ladwa (2015) was used as key study for the PNEC derivation (K-score of 1). The acute toxicity of the substance was tested using the rainbow trout as test species. The test was conducted according to the threshold approach recommended by ECHA.
Using this approach the lowest EC50 value from either the Algal Growth Inhibition study or Acute toxicity to Daphnia magna study is set as the threshold concentration and a limit test is conducted at this threshold concentration.Analysis of the test preparation at 0, 24, 72 and 96 hours showed measured concentrations to range from 88% to 98% of the nominal values respectively, so the results are based on nominal test concentrations.
No mortality was observed after 96 hours at a test concentration of 49 mg a.i./L. Therefore the LC50 was set to > 49 mg a.i./L.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
