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Diss Factsheets
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EC number: 903-161-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
EC 903-161-3 is a substance of unknown, variable composition or biological origin (UVCB).
The substance is poorly soluble in water and therefore abiotic hydrolysis is not a relevant pathway.
In the key persistence study (2016 OECD 301B), EC 903-161-3 was shown to undergo biotic and abiotic degredation, but did not fulfil the criteria for ready biodegredability. Due to the test items low water solubility, silica gel was used to enhance the availability to the inoculum, the study was also extended to 60 days to investigate the inherent degradation potential of the test item. A mean total of 49.5% degradation was achieved. The average biotic and abiotic cumulative percent biodegradation for EC 903-161-3 were 6.4% and 43.1% respectively. EC 903-161-3 may not be considered readily biodegradable, since 60% TCO2 was not achieved within 10 days of achieving 10% TCO2. Based on these findings it was concluded that the test item was not readily biodegradable.
The substance has a log Koc > 3 indicating a potential to adsorb to soil and sediment particles. Due to its low water solubility (< 0.5 mg/L in water) and potential for adsorption to soil and sediment particles, only low concentrations of the substance are expected to be released into the aquatic environment. The substance will be bioavailable to aquatic organisms mainly via feed and contact with suspended organic particles. EC 903-161-3 is not bioaccumulative, based on the criteria given in Regulation (EC) No. 1907/2006, Annex XIII, 1.1.2 (BCF < 2000 L/kg). This assessment is based on BCF/BAF values estimated with the BCFBAF v3.01 program, calculated for representative structures of this UVCB, as well as the high log Kow ( > 10; KOWWIN v1.68).
In conclusion, based on the current data, EC 903-161-3 is not rapidly removed by biotic degradation processes. Due the low water solubility and high adsorption potential, the main route of exposure for aquatic organisms such as fish will be via food ingestion or contact with suspended solids.In addition, available data indicate that this substance is not bioaccumulative.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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