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EC number: 603-493-6 | CAS number: 131560-11-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
- Report date:
- 2001
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- triphenyl[(2E,4E,6E)-3,7,11-trimethyldodeca-2,4,6,10-tetraen-1-yl]-λ⁵-phosphane
- EC Number:
- 603-493-6
- Cas Number:
- 131560-11-7
- Molecular formula:
- C33 H38 P
- IUPAC Name:
- triphenyl[(2E,4E,6E)-3,7,11-trimethyldodeca-2,4,6,10-tetraen-1-yl]-λ⁵-phosphane
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- The concentration control analyses were performed with test solutions of the following nominal concentrations (mg/l) of the test substance: control (0 mg/L), 1 and 0.125 mg/L
At the start of the test (after 0 h) and at the end of the test (after 48 h) samples from vesseis without daphnids were analysed.
Test solutions
- Vehicle:
- no
- Details on test solutions:
- The test substance was stirred in M4 medium for about 10 minutes at 20 ± 2 0C.
The nominal concentration of the stock solution was 100 mg/l.
By diluting this stock solution with M4 medium the following nominal concentrations (mg/I) were prepared: control (0 mg/L), 0.008, 0.016, 0.031, 0.063, 0.125, 0.25, 0.5, 1 mg/L
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Water flea
- Strain/clone: The clone of Daphnia magna STRAUS 1820 used was supplied by the Institut National de Recherche Chimique AppIiquäe, France, in 1978. From this date on this clone was cultured and bred continuously in the Laboratory Experimental Toxicology and Ecology of BASF AG in Ludwigshafen.
- Justification for species other than prescribed by test guideline: not applicable
- Age at study initiation (mean and range, SD): 2 - 24 h
- Method of breeding: grouped culture
- Source: The clone of Daphnia magna STRAUS 1820 used was supplied by the Institut National de Recherche Chimique AppIiquäe, France, in 1978. From this date on this clone was cultured and bred continuously in the Laboratory Experimental Toxicology and Ecology of BASF AG in Ludwigshafen.
- Age of parental stock (mean and range, SD): 2 - 4 weeks
- Feeding during test: no
ACCLIMATION
- Acclimation period: not applicable
- Acclimation conditions (same as test or not): yes
- Type and amount of food: green algae
- Feeding frequency: daily
- Health during acclimation (any mortality observed): not indicated
Study design
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 2.33 mmol/ L
- Test temperature:
- 20.4 - 20.6 °C
- pH:
- 8.1 - 8.2
- Dissolved oxygen:
- 8.3 - 8.6 mg/L
- Conductivity:
- 611 µS/cm
- Nominal and measured concentrations:
- nominal: 0, 0.008, 0.016, 0.031, 0.063, 0.125, 0.031, 0.25, 0.5, 1 mg/L
measured analytical concentrations at test start (0 h) in % of nominal: 48 - 70
measured analytical concentrations at test end (48 h) in % of nominal: 32 - 50 - Details on test conditions:
- TEST SYSTEM
- Test vessel: flat bottom glass tubes (nominal 20 ml)
- Type (delete if not applicable): open / closed
- Material, size, headspace, fill volume: glass, nominal 20 ml
- Volume of solution: 10 ml
- Aeration: no
- Renewal rate of test solution (frequency/flow rate): static test, no renewal of test medium
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 4
- No. of vessels per control (oxygen measurement): 1
- No. of vessels per control (analytical measurement): 2
- Biomass loading rate: 0.5 animals/L
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: M4-medium according to OECD 202
OTHER TEST CONDITIONS
- Adjustment of pH: no
- Photoperiod: 16:8 h day night regime
- Light intensity: About 2 - 7 pE/(m 2.s) at a wave length of 400 - 700 nm
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : 0, 24 and 48 h (mobility)
VEHICLE CONTROL PERFORMED: no
- Reference substance (positive control):
- yes
- Remarks:
- reference material was tested at regular intervals
Results and discussion
Effect concentrations
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.032 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Reported statistics and error estimates:
- For the statistical calculation of the EC50 the moving average method was used.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
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