Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 419-340-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
Emergency measure - Inhalation: Remove subject to fresh air. Give artificial respiration if
breathing has stopped. Seek immediate medical attention.
Emergency measure - Eyes: Wash with copious amounts of water for 15-20 minutes. Seek
medical attention.
Emergency measure - Skin: Remove contaminated clothing and wash affected area with
soap and water for at least 15 minutes. Seek medical
attention if irritation develops or persists.
Emergency measure - Ingestion: Seek medical attention immediately. Rinse mouth thoroughly
with water if the subject is conscious. Vomiting may be
induced if person is conscious, is not experiencing
convulsions and if ingestion has occurred within the
previous 3 hours. Do not induce vomiting if the person is
unconscious.
Fire-fighting measures
Recommended extinguishing agent: Use agents appropriate for surrounding environment. Water
or foam are suitable.
Product arising from burning: May include CO, CO2 and oxides of nitrogen.
Product determined by test: N
Protective equipment: Full protective clothing, with self contained breathing
apparatus must be worn.
Accidental release measures
Emergency measures in case of spillage: Protective clothing and a respirator must be worn by
operators cleaning up any spillage.
Collect material to minimise dust generation; use wet mop,
damp sponge or wet/dry HEPA vacuum. Place collected
substance into a suitable container for disposal. Spill
area should be washed and well ventilated.
Handling and storage
Handling: When engineering controls are not sufficient to control dust
exposure, approved respiratory protection to EN 136 standard
should be worn. For manufacturing areas, skin protection
should be provided in the form of overalls, or full air
suits along with latex or other impermeable gloves. Rubber,
neoprene or other gloves may be required if solvents,
corrosives or other chemicals are present. Chemical safety
glasses should be worn if a full face respirator is not
being worn.
Storage: Store in sealed, upright containers in a dry area away from
heat sources. Ensure containers are correctly labelled.
Packaging of the substance and or preparation: Fibre drums (47 x 72 cm). 34kg maximum capacity. UN
approved.
Transport information
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Marine transport (UN RTDG/IMDG)
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Air transport (UN RTDG/ICAO/IATA)
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Special provisions / remarks
- Remarks:
- Transport code: No UN number has been assigned.
Transport: Use normal procedures for transport of industrial chemicals
not considered hazardous for transport. Ensure the
containers are securely held to prevent falling over.
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Exposure controls / personal protection
Stability and reactivity
Danger other than fire: None known.
Chemical reaction with water: None known.
Dust explosion: Compound has been tested as a combustible dust with a class
ST-2 explosion strength (ASTM E 1226 Method). As with any
organic material, a suspended dust cloud of the substance
may ignite if subject to a strong ignition source or static
electricity. Provide appropriate bonding and grounding to
control static charges.
Dust explosion determined by test: Y
Disposal considerations
Industry - Possibility of recovery/recycling: BMS-183981-01 is consumed in the drug synthesis reaction in
which it is employed. Significant residue levels in the
reactor effluent are not expected. No practical means of
recovery or recycling are known.
Industry - Possibility of neutralisation: No method of neutralization is known.
Industry - Possibility of destruction: controlled discharge: Trace quantities are destroyed by biological oxidation in
the wastewater treatment plant prior to discharge to the
sewage system. (A641)
Industry - Possibility of destruction - incineration: Incineration is recommended for larger quantities. A
closed-cycle incinerator with scrubbers should be employed.
National regulations must be observed. (A663)
Industry - Possibility of destruction - water purification: Trace quantities of material in aqueous washes and in other
liquors will be treated in secondary biological waste water
treatment plant before discharge to sewage works.
Industry - Possibility of destruction - other: None
Public at large - Possibility of recovery/recycling: Not applicable. The material is a chemical intermediate for
the pharmaceutical industry and is not intended for public
use.
Public at large - Possibility of neutralisation: Not applicable
Public at large - Possibility of destruction: controlled discharge: Not applicable
Public at large - Possibility of destruction - incineration: Not applicable
Public at large - Possibility of destruction - water purification: Not applicable
Public at large - Possibility of destruction - others: Not applicable
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.