Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 248-451-4 | CAS number: 27425-55-4
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
72 hrs aquatic toxicity study was predicted (SSS QSAR Prediction model, 2016) to assess toxic effects of the test compound 3-(1H-benzimidazol-2-yl)-7-(diethylamino)-2-benzopyrone (CAS No. 27425-55-4) and the results were predicted. The study was based on the effects of the test compound on Pseudokirchnerella subcapitata in a static fresh water system. The predicted data suggests the effective concentration (EC50) for the test compound 3-(1H-benzimidazol-2-yl)-7-(diethylamino)-2-benzopyrone (CAS No. 27425-55-4) was estimated to be 15.956 mg/l on the basis of growth rate. Thus based on this value, it can be concluded that the substance can be classified as aquatic chronic category 3. Since the test chemical is readily biodegradable in nature, test chemical 3-(1H-benzimidazol-2-yl)-7-(diethylamino)-2-benzopyrone can be considered as non-toxic to aquatic organisms and thus cannot be classified as hazardous as per the CLP criteria.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 15.95 mg/L
Additional information
72 hrs aquatic toxicity study was predicted (SSS QSAR Prediction model, 2016) to assess toxic effects of the test compound 3-(1H-benzimidazol-2-yl)-7-(diethylamino)-2-benzopyrone (CAS No. 27425-55-4) and the results were predicted. The study was based on the effects of the test compound on Pseudokirchnerella subcapitata in a static fresh water system. The predicted data suggests the effective concentration (EC50) for the test compound 3-(1H-benzimidazol-2-yl)-7-(diethylamino)-2-benzopyrone (CAS No. 27425-55-4) was estimated to be 15.956 mg/l on the basis of growth rate. Thus based on this value, it can be concluded that the substance can be classified as aquatic chronic category 3. Since the test chemical is readily biodegradable in nature, test chemical 3-(1H-benzimidazol-2-yl)-7-(diethylamino)-2-benzopyrone can be considered asnon-toxic to aquatic organisms and thus cannot be classified as hazardous as per the CLP criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
