Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 232-318-2 | CAS number: 8003-22-3 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 47000.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- no data: aquatic toxicity unlikely
Marine water
- Hazard assessment conclusion:
- no data: aquatic toxicity unlikely
STP
- Hazard assessment conclusion:
- no data: aquatic toxicity unlikely
Sediment (freshwater)
- Hazard assessment conclusion:
- insufficient hazard data available (further information necessary)
Sediment (marine water)
- Hazard assessment conclusion:
- insufficient hazard data available (further information necessary)
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- insufficient hazard data available (further information necessary)
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Classification of 1, 3-isobenzofurandione, reaction products with methyl quinoline and quinoline for effects in the environment
In determining the classification appropriate to1,3-isobenzofurandione, reaction products with methyl quinoline and quinoline, it is necessary to consider all available evidence concerning its persistence, potential to accumulate and predicted or observed environmental fate and behaviour that may present a long-term and/or delayed danger to the structure and/or functioning of aquatic ecosystems. These points are considered below.
Persistence
Reliable studies are available to demonstrate that 1,3-isobenzofurandione, reaction products with methyl quinoline and quinoline is non-persistent in nature (i.e. water, sediment and soil) and so is considered to be biodegradable in the environment. In other words 1,3-isobenzofurandione, reaction products with methyl quinoline and quinoline may therefore be expected to degrade rapidly. Thus it can be inferred that 1,3-isobenzofurandione, reaction products with methyl quinoline and quinoline is non-persistent.
1,3-isobenzofurandione, reaction products with methyl quinoline and quinoline is non-persistent and does not satisfy the criteria for classification as persistent (P).
Bioaccumulation
Thought the estimated log Kow values for 1,3-isobenzofurandione, reaction products with methyl quinoline and quinoline is greater than 4 (Log Kow = 4.1). The potential for 1,3-isobenzofurandione, reaction products with methyl quinoline and quinoline to bioaccumulate in the tissues of organisms that inhabit aquatic or terrestrial matrices is negligible as the BCF factor for the substance is less than 2000. The estimated BCF of 1,3-isobenzofurandione, reaction products with methyl quinoline and quinoline is highest 61.25 dimensionless and below the threshold of 2000.
Thus 1,3-isobenzofurandione, reaction products with methyl quinoline and quinoline does not satisfy the criterion for classification as bio accumulative (B).
Toxicity
The aquatic toxicity profile for the chemical, 1,3-isobenzofurandione, reaction products with methyl quinoline and quinolone cannot be established as the substance is poorly soluble as so long term study will have required for finalization. Further the short term values cannot be considered as valid since no mortality was observed even at a range below the low solubility (a substance will not be present in solution at a concentration above its solubility, unless solubilized by other substances). Thus, as on date the aquatic toxicity is considered as negative considering the BCF criteria of <500 for the chemical.
So, 1,3-isobenzofurandione, reaction products with methyl quinoline and quinolinedoes not satisfy the environmental effects criterion for classification as toxic (T).
Further as per Annex XIII of the REACH regulation it can be inferred that1,3-isobenzofurandione, reaction products with methyl quinoline and quinolineis not a PBT (including vPvB) substance.
Conclusion on classification
Classification is not triggered based on available data, according to REGULATION (EC) No 1272/2008 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.