Registration Dossier
Registration Dossier
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EC number: 228-055-8 | CAS number: 6104-30-9
Sediment toxicity
Administrative data
Link to relevant study record(s)
- Endpoint:
- sediment toxicity: long-term
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Reference
Description of key information
Since for N,N''-(isobutylidene)diurea (CAS 6104-30-9) the log Kow is < 3, no persistence and thus no long-term exposure of sediment organisms is expected and no toxicity was determined in acute aquatic toxicity test, no toxicity study with sediment organisms is needed
Key value for chemical safety assessment
Additional information
N,N''-(isobutylidene)diurea (CAS 6104-30-9) is characterized by a log Kow < 3 (log Kow = -0.903 at 23°C). According to chapter R. 7b of the ‘Guidance on information requirements and chemical safety assessment' (ECHA, 2017) a log Kow of 3 is defined as a trigger value for a sediment assessment. The log Kow of N,N''-(isobutylidene)diurea (CAS 6104-30-9) is -0.903 and thus < 3. Therefore, no adsorbtion to sediment is expected and no sediment testing is needed.
Furthermore, the substance is readily biodegradable and thus expected to be extensively removed from water in sewage treatment plants. As mentioned in the Guidance on Information Requirements and Chemical Safety Assessment, Chapter R.7b (ECHA, 2017), the ready biodegradability of a substance can be an indication of rapid and ultimate degradation in most environments, including biological sewage treatment plants (STP). Due to the ready biodegradation, it is assumed that the discharged concentration of N,N''-(isobutylidene)diurea (CAS 6104-30-9) in the effluent of conventional STPs is negligible. Thus, insignificant release into the aqueous compartment and thus also in the sediment compartment is expected. Furthermore, the substance is expected to undergo rapid and ultimate degradation if released into the water compartment. Thus, persistence and thus long-term exposure of sediment organisms is not expected due to the ready biodegradability of the substance.
Moreover, the available acute aquatic toxicity tests with freshwater organisms demonstrated that the substance show no toxicity to aquatic organisms. Thus, toxicity is also not expected for sediment organisms.
In conclusion, since for N,N''-(isobutylidene)diurea (CAS 6104-30-9) the log Kow is < 3, no persistence and thus no long-term exposure of sediment organisms is expected and no toxicity was determined in acute aquatic toxicity test, no toxicity study with sediment organisms is needed.
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