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Diss Factsheets
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EC number: 214-688-7 | CAS number: 1185-81-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
Description of key information
The water solubility of the test item has been determined to be in the range 3.22 x 10-4 to 5.74 x 10-4 g/l of solution at 20.0 ± 0.5°C when applying the standard saturation and equilibration times specified within the test method guidelines, with a decreasing concentration observed on extension of the initial saturation period. Testing used a flask method, designed to be compatible with Method A6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
On applying a significantly reduced initial saturation period and final equilibration period of 1 hour at each stage, the resulting solubility was elevated to 6.26 x 10-4 g/l of solution at 20.0 ± 0.5°C. The maximum observed solubility of 9.90 x 10-4 g/l of solution at 20.0 ± 0.5°C was observed for the preliminary test where the initial saturation period and final equilibration period were 18½ hours and 3½ hours respectively.
However, analytical data may systematically overestimate the solubility of the parent test item, as although a chromatographic peak was resolved by the analytical method, even on the application of a mass selective detector, the analytical method may not have been substance specific to the test item. Organotin compounds, due to thermal instability, do not result in a detectable parent mass ion on analysis. The ion monitored analytically was that of a tin adduct with tropolone (introduced as a mobile phase additive), and therefore although analytical data did confirm the presence of a soluble, tin containing compound, it may have been influenced by the presence of more soluble tin containing impurities and/or hydrolysis products.
Key value for chemical safety assessment
Additional information
Vaue for CSA: In the range 3.22 x 10-4 to 5.74 x 10-4 g/l of solution at 20.0 ± 0.5°C
A reliability rating of 1 was assigned to the key study according to the criteria of Klimisch, 1997 as the study was conducted in accordance with recognised guidelines and GLP.
According to the EU Directive 67/548/EEC, a poorly soluble substance can be defined as a substance with a solubility of less than 1 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.