Registration Dossier
Registration Dossier
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EC number: 212-141-7 | CAS number: 765-14-0
Water solubility
Administrative data
Link to relevant study record(s)
Description of key information
The water solubility of the test item cannot be evaluated quantitatively since it was not possible to receive stable values for the water solubility of the test item.
Key value for chemical safety assessment
Additional information
Weight of evidence approach
The water solubility of the test item was determined according to OECD guideline for Testing of Chemicals 105, flask method by using a slow stirring speed in large flasks as depicted in in OECD Guideleine for Testing of Chemicals 123, Partition Coefficient (1-Octanol/Water): Slow-Stirring Method on page 15 (BASF SE, 2017). Approximately 75 mg and 162 mg of the test item were filled into a glass-jacketed vessel with an outlet valve at the bottom of the vessel and were mixed each with 500 mL of water (preparation 0.15 g/L and preparation 0.32 g/L). After adding a glass stopper, the preparations were shortly shaken and then stirred at 20 °C with a stirring rate of 300 rpm for 9 h. The stirring rate was reduced to 200 rpm for the remaining stirring time. In total, the preparations were stirred for 25, 29, 48.5, 54, 72, 96 and 218 h. The values determined for the water solubility of the test item decrease over time. In addition, the different amounts of surplus in the preparations (0.15 g/L and 0.32 g/L) resulted in different concentrations: The preparation with 0.32 g/L of surplus resulted in increased concentrations compared to the preparation with 0.15 g/L of surplus. However, determination of the water solubility according to OECD Guideline 105 was technically not feasible since it was not possible to receive stable values for the water solubility of the test item.
In addition, a literature review was conducted and the Handbook of Paint and Coating Raw Materials (Knovel, 2014) report the test item to be soluble in water.
In conclusion, the test substance is considered to be soluble in water as cited in Knovel (2014).
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