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EC number: 209-378-3 | CAS number: 574-93-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to soil macroorganisms except arthropods: short-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 207 (Earthworm, Acute Toxicity Tests)
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Name of test material (as cited in study report): Heliogen Gruen 8730 Pulver;
- Source and lot/batch number of test material: BW137(Partien 616-619)
- Analytical purity: > 98%, Impurities: 0.11% water
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: ambient - Analytical monitoring:
- no
- Vehicle:
- no
- Details on preparation and application of test substrate:
- The test substance was weighed and added directly to each parallel. No dilution series was prepared
- Test organisms (species):
- Eisenia fetida
- Animal group:
- annelids
- Details on test organisms:
- TEST ORGANISM
- Common name: Eisenia fetida (Michaelsen)
- Source:
- Age at test initiation (mean and range, SD): 9 months
- Weight at test initiation (mean and range, SD): 300 - 600 mg
ACCLIMATION
- Acclimation period: 24 h before the test, in test substrate without test substance
- Acclimation conditions (same as test or not): same - Study type:
- laboratory study
- Substrate type:
- artificial soil
- Limit test:
- no
- Total exposure duration:
- 14 d
- Test temperature:
- 19.3 - 20.3 °C
- pH:
- 6.3
- Moisture:
- - water content(day 0): 1563.8 g (33.3 %) - water content(day 14): 1561.6 g (33.2 %)
- Details on test conditions:
- TEST SYSTEM
- Test container (material, size): 1l glass jars with glass lids
- Amount of soil or substrate: 750 g artificial soil (dry weight)
- No. of organisms per container (treatment): 10
- No. of replicates per treatment group: 4
- No. of replicates per control: 4
- No.r of parallels without animals: 1 (determination of the water content, pH and temperature measurement)
SOURCE AND PROPERTIES OF SUBSTRATE (if soil)
- Soil texture (if natural soil)
- % sand: 69.7
- % sphagnum peat: 10
- % clay: 20
OTHER TEST CONDITIONS
- Light intensity: continuous illumination, about 400 - 800 lux
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : mortality after 7 and 14 days, (inhibition of the biomass)
VEHICLE CONTROL PERFORMED: no
- Nominal and measured concentrations:
- Nominal: 0, 62.5, 125, 250, 500, 1000 mg/kg
- Key result
- Duration:
- 14 d
- Dose descriptor:
- LC50
- Effect conc.:
- > 1 000 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- >= 1 000 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Details on results:
- The short hatching of the earthworms before introduction in the test was carried out with a pH-value of 4.1. However this has no influence on the EC-value of the reference substance, the weight and the clitellum of the earthworms.
- Validity criteria fulfilled:
- yes
Reference
Validity criteria:
- The mortality in the controls did not exceed 10 % at the end of the test.
- The LG50 <14d) of the control substance chloracetamide was 25,9 mg/kg.
Description of key information
The substance is not toxic to soil microorganisms except arthropods, with an LC50 > 1000 mg/kg soil dey weight.
Key value for chemical safety assessment
- Short-term EC50 or LC50 for soil macroorganisms:
- 1 000 mg/kg soil dw
Additional information
All substances in this category share a similar structure with a molecular weight > 500 g/mol. Based on the high molecular weight and insolubility, the substances in this category will not be able to penetrate biological membranes. Thus, no systemic exposure is expected. This is confirmed by the environmental studies on soil microorganisms except arthropods for one substance in this category: CAS 1328-53-6. The environmental toxicity data can be used for read-across to all substances in this category.
In a guideline study according to OECD TG 207 on Eisenia foetida, the substance CAS 1328-53-6 was mixed with artificial soil, and the earthworms were kept on the soil/substance mixture for 14 days. The 14-d NOEC was determined to be ≥ 1000 mg/kg soil (BASF 2000, K2). The results indicate that the substance is not toxic to soil macroorganisms (arthropods excluded).
In addition to the experimental data, all substances in this category have a low potential for adsorption to soil and no bioaccumulative properties. Therefore, binding to sewage sludge is unlikely. Consequently, a transfer to the soil compartment is not expected. The lack of harmful effects to all three trophic levels of aquatic organisms at concentrations below the solubility in water indicates a low hazardous potential of the test substance towards soil organisms. Based on the available information, it is concluded that all substances in this category are not toxic to soil microorganisms except arthropods, with an LC50 > 1000 mg/kg soil dry weight.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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