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EC number: 201-116-6 | CAS number: 78-42-2
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 26 November 2015 to 13 December 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- The study was conducted in accordance with international guidelines and in accordance with GLP. All relevant validity criteria were met.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: Knudsen cell
- Key result
- Test no.:
- #1
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Test no.:
- #1
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Vapour pressure:
- 0.002 Pa
- Transition / decomposition:
- no
- Conclusions:
- The vapour pressure was determined to be 2.3E-05 Pa (20 °C).
- Executive summary:
The vapour pressure of the test item was determined in accordance with EC Method A.4 (Vapour Pressure, Effusion Method) and OECD 104 (Vapour Pressure) using a Knudsen Cell (Dornhagen, 2016). The vapour pressure was determined to be 2.3E-05 Pa (20 °C).
Reference
Table 1. Measured Vapour pressures and Corresponding Temperatures
| Temperature (°C) | Vapour Pressure (hPa) |
| 30 | 1.6E-05 |
| 40 | 5.9E-05 |
| 50 | 1.1E-04 |
| 60 | 1.3E-04 |
| 70 | 2.3E-04 |
| 75 | 3.2E-04 |
| 80 | 5.4E-04 |
| 85 | 9.1E-04 |
| 90 | 1.5E-03 |
| 95 | 2.6E-03 |
| 100 | 4.2E-03 |
The data points measured at 30 to 70 °C were not included in the linear regression because they showed a typical deviation caused by volatile impurities at the beginning of a measurement.
Vapour pressure (logarithmic scale) was plotted as a function of the inverse temperature (1/T, T in Kelvin). The values for 20, 25 and 50 °C were calculated, using the Antoine Constants A, B and C as shown in Table 2.
Table 2. Antoine Parameters and Extrapolated Vapour Pressures
| T / °C | p / hPa | log (p/hPa) = A + B/C+T[°C]) |
| 20 | 2.3E-07 | A = 13.21121 |
| 25 | 5.0E-07 | B = -5817.72 |
| 50 | 1.6E-05 | C = 273.15 |
Description of key information
Vapour Pressure = 2.3E-05 Pa (20 °C); OECD 104; Dornhagen (2016)
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 20 °C
Additional information
In a single key study, the vapour pressure of the test item was determined in accordance with EC Method A.4 (Vapour Pressure, Effusion Method) and OECD 104 (Vapour Pressure) using a Knudsen Cell (Dornhagen, 2016). The vapour pressure was determined to be 2.3E-05 Pa (20 °C).
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