EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

This list contains a non-exhaustive inventory of substances that fall within the scope of the European Union's definition of hazardous chemical and biological substances, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; and (2) Annex III of Directive 2000/54/EC (Biological Agents). The EU's Occupational Safety and Health (OSH) Framework Directive 89/391/EEC applies to risks arising from chemical, physical and biological agents at the workplace.

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Last updated 18 april 2024. Database contains 4691 unique substances/entries.
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Substance Name
EC No.
CAS No.
EU CLP (1272/2008)
EU_BA Directive 2000/54/EC
trisodium [4'-(8-acetylamino-3,6-disulfonato-2-naphthylazo)-4''-(6-benzoylamino-3-sulfonato2-naphthylazo)-biphenyl 1,3',3'',1'''-tetraolato-O,O',O'',O''']copper(II)
SOLAMINLICHTBLAU VGRL 133
413-590-3
164058-22-4
Carc. 1B
trisodium bis(2-(5-chloro-4-nitro-2-oxidophenylazo)-5-sulphonato-1-naphtholato)chromate(1-)
ACID BLUE 349; AZO-METALCOMPLEX-BLUE AP 1149; BLEU ACIDE 349; C.I. ACID BLUE 349; SELLASET BLEU H; SELLASET BLUE H
402-870-0
93952-24-0
Eye Dam. 1
trisodium bis(7-acetamido-2-(4-nitro-2-oxidophenylazo)-3-sulphonato-1-naphtholato)chromate(1-)
BI 3277; NOIR CORSE SANODAL H3LW CONC.; SANODAL DEEP BLACK H-3LW CONC.; SANODAL TIEFSCHWARZ H-3LW; SANODAL TIEFSCHWARZ H-3LW KONZ.
400-810-8
106084-79-1
Muta. 2
trisodium bis[(3'-nitro-5'-sulfonato(6-amino-2-[4-(2-hydroxy-1-naphtylazo)phenylsulfonylamino]pyrimidin-5-azo)benzene-2',4-diolato)]chromate(III)
RED JB 747
418-220-4
-
Skin Sens. 1
trisodium hexafluoroaluminate
237-410-6
13775-53-6
STOT RE 1; Acute Tox. 4
trisodium hexafluoroaluminate(cryolite)
239-148-8
15096-52-3
STOT RE 1; Acute Tox. 4
trisodium N, N-bis(carboxymethyl)-3-amino-2-hydroxypropionate
TRILON(R) ES 9910
414-130-4
119710-96-2
Acute Tox. 4
trisodium N, N-bis(carboxymethyl)-β-alanine
TRILON(R) ES 9851
414-070-9
129050-62-0
Skin Corr. 1B
trisodium N-(3-propionato)-l-aspartate
422-090-4
172737-80-3
Eye Dam. 1
trisodium nitrilotriacetate
225-768-6
5064-31-3
Carc. 2; Acute Tox. 4; Eye Irrit. 2
trisodium(2-(α-(3-(4-chloro-6-(2-(2-(vinylsulfonyl)ethoxy)ethylamino)-1,3,5-triazin-2-ylamino)-2-oxido-5-sulfonatophenylazo)benzylidenehydrazino)-4-sulfonatobenzoato)copper(II)
REACTIVE BLUE 245
407-580-8
130201-51-3
Eye Dam. 1
triticonazole (ISO); (RS)-(E)-5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-methyl)cyclopentanol
-
138182-18-0
Repr. 2; STOT RE 2
tritosulfuron (ISO) (containing ≤0,02 % AMTT); 1-[4-methoxy-6-(trifluoromethyl)-1,3,5-triazin-2-yl]-3-[2-(trifluoromethyl)benzenesulfonyl]urea (containing ≤ 0,02 % AMTT)
604-291-0
142469-14-5
Skin Sens. 1
trixylyl phosphate
246-677-8
25155-23-1
Repr. 1B
trizinc diphosphide; zinc phosphide
215-244-5
1314-84-7
Water-react. 1; Acute Tox. 2
troclosene potassium
218-828-8
2244-21-5
Ox. Sol. 2; Acute Tox. 4; Eye Irrit. 2; STOT SE 3
troclosene sodium
220-767-7
2893-78-9
Ox. Sol. 2; Acute Tox. 4; Eye Irrit. 2; STOT SE 3
troclosene sodium, dihydrate
610-700-3
51580-86-0
Acute Tox. 4; Eye Irrit. 2; STOT SE 3
Trypanosoma brucei brucei
-
-
P Parasites
Trypanosoma brucei gambiense
-
-
P Parasites
Trypanosoma brucei rhodesiense
-
-
P Parasites
Trypanosoma cruzi
-
-
P Parasites
trypsin
232-650-8
9002-07-7
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
turpentine, oil
Any of the volatile predominately terpenic fractions or distillates resulting from the solvent extraction of, gum collection from, or pulping of softwoods. Composed primarily of the C10H16 terpene hydrocarbons: α-pinene, β-pinene, limonene, 3-carene, camphene. May contain other acyclic, monocyclic, or bicyclic terpenes, oxygenated terpenes, and anethole. Exact composition varies with refining methods and the age, location, and species of the softwood source.
232-350-7
8006-64-2
Flam. Liq. 3; Acute Tox. 4; Asp. Tox. 1; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
uranium
231-170-6
7440-61-1
Acute Tox. 2; STOT RE 2
uranium compounds with the exception of those specified elsewhere in this Annex
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Uranium ditelluride EC / List no: 235-249-6 | CAS no: 12138-37-3
Zinc tetrakis(acetato-O)dioxouranate EC / List no: 251-762-8 | CAS no: 33959-50-1
Difluorodioxouranium EC / List no: 236-898-8 | CAS no: 13536-84-0
Bis(formato-O)dioxouranium EC / List no: 241-063-6 | CAS no: 16984-59-1
Dipotassium uranyl bis(sulphate), of uranium depleted in uranium-235 EC / List no: 262-284-4 | CAS no: 60542-74-7
Bis(nitrato-O)dioxouranium EC / List no: 233-266-3 | CAS no: 10102-06-4
Nitric acid, uranium(6+) salt EC / List no: - | CAS no: 20820-60-4
Calcines, uranium ore-conc.
Calcined precipitates of ammonium, magnesium or sodium uranates obtained from natural uranium ores.
EC / List no: 297-819-0 | CAS no: 93763-02-1
Uranium tetrafluoride EC / List no: 233-170-1 | CAS no: 10049-14-6
Dioxobis(pentane-2,4-dionato-O,O')uranium EC / List no: 241-951-3 | CAS no: 18039-69-5
Uranium tetraboride EC / List no: 234-520-6 | CAS no: 12007-84-0
Disodium heptaoxodiuranate, of uranium depleted in uranium-235 EC / List no: 237-286-3 | CAS no: 13721-34-1
Titanate(4-), oxobis[phosphato(3-)]-, barium (1:2), uranium-doped EC / List no: 309-550-9 | CAS no: 100403-10-9
Uranium disilicide EC / List no: 234-906-4 | CAS no: 12039-85-9
Sodium tris(benzeneacetato-O)dioxouranate(1-) EC / List no: 309-040-6 | CAS no: 99800-13-2
Uranium diselenide EC / List no: 235-245-4 | CAS no: 12138-21-5
Zinc bis(acetato-O)dioxouranate EC / List no: 233-390-8 | CAS no: 10138-94-0
Uranium carbide (UC2) EC / List no: - | CAS no: 12071-33-9
Nasturan EC / List no: 690-098-7 | CAS no: 1317-99-3
Uranium disulphide EC / List no: 234-884-6 | CAS no: 12039-14-4
Uranium dioxide EC / List no: 215-700-3 | CAS no: 1344-57-6
Triuranium tetraphosphide EC / List no: 234-871-5 | CAS no: 12037-84-2
Uranium tetrachloride EC / List no: 233-057-7 | CAS no: 10026-10-5
Tetraammonium uranyl tricarbonate, of uranium depleted in uranium-235 EC / List no: 241-988-5 | CAS no: 18077-77-5
Resin acids and Rosin acids, uranyl salts EC / List no: 273-325-0 | CAS no: 68956-97-8
Hydrogen dioxo[phosphato(3-)-O,O']uranate(1-) EC / List no: 242-306-9 | CAS no: 18433-48-2
Uranium carbide (UC) EC / List no: - | CAS no: 12070-09-6
Uranium trifluoride EC / List no: 237-404-3 | CAS no: 13775-06-9
Magnesium uranium(4+) hexaacetate EC / List no: 243-905-8 | CAS no: 20596-93-4
Uranium tetrabromide EC / List no: 236-734-5 | CAS no: 13470-20-7
Uranate(2-), tetrakis(acetato-O)-dioxo-, magnesium (1:1), (OC-6-11)- EC / List no: - | CAS no: 66735-86-2
Uranium fluoride (U2F9) EC / List no: - | CAS no: 12134-48-4
Uranyl acetate-2H2O EC / List no: 629-550-5 | CAS no: 6159-44-0
Uranium hexafluoride EC / List no: 232-028-6 | CAS no: 7783-81-5
Nickel uranyl tetraacetate, of uranium depleted in uranium-235 EC / List no: 275-994-4 | CAS no: 71767-12-9
Dipotassium heptaoxodiuranate EC / List no: 232-217-3 | CAS no: 7790-63-8
Bis(2-ethylhexanoato-O)dioxouranium EC / List no: 267-849-9 | CAS no: 67939-77-9
Uranium pentafluoride EC / List no: 237-405-9 | CAS no: 13775-07-0
Lead uranate pigment EC / List no: 287-565-9 | CAS no: 85536-79-4
Sodium uranyl triacetate, of uranium depleted in uranium-235 EC / List no: 241-714-4 | CAS no: 17712-38-8
Dichlorodioxouranium EC / List no: 232-246-1 | CAS no: 7791-26-6
Uranium dioxideperoxide EC / List no: 234-852-1 | CAS no: 12036-71-4
Uranium diboride EC / List no: 234-508-0 | CAS no: 12007-36-2
Uranium hydride EC / List no: 257-346-2 | CAS no: 51680-55-8
Diammonium diuranium heptaoxide EC / List no: 231-986-2 | CAS no: 7783-22-4
Uranium EC / List no: 231-170-6 | CAS no: 7440-61-1
Nitric acid, uranium salt EC / List no: - | CAS no: 15905-86-9
Uranium triiodide EC / List no: 237-406-4 | CAS no: 13775-18-3
Tetrakis(pentane-2,4-dionato-O,O')uranium EC / List no: 265-498-6 | CAS no: 65137-03-3
Disodium uranium tetraoxide EC / List no: 236-846-4 | CAS no: 13510-99-1
Oxobis(pentane-2,4-dionato-O,O')uranium EC / List no: 254-311-3 | CAS no: 39136-40-8
Calcium diuranium heptaoxide EC / List no: 237-428-4 | CAS no: 13780-21-7
Dioxo[sulphato(2-)-O]uranium EC / List no: 215-240-3 | CAS no: 1314-64-3
Uranium hydride (UH3) EC / List no: - | CAS no: 13598-56-6
Uranium trioxide EC / List no: 215-701-9 | CAS no: 1344-58-7
Uranium tetraiodide EC / List no: 236-735-0 | CAS no: 13470-22-9
polysilicate EC / List no: - | CAS no: 12427-14-4
Barium uranium oxide EC / List no: - | CAS no: 10380-31-1
Magnesium diuranium heptaoxide EC / List no: 236-982-4 | CAS no: 13568-61-1
Nickel triuranium decaoxide EC / List no: 239-876-6 | CAS no: 15780-33-3
Bis(nitrato-O,O')dioxouranium EC / List no: 253-053-9 | CAS no: 36478-76-9
Acetic acid, uranium(4+) zinc salt EC / List no: 243-904-2 | CAS no: 20596-91-2
Uranium nitrate EC / List no: - | CAS no: 13826-82-9
Bis(acetato-O)dioxouranium EC / List no: 208-767-5 | CAS no: 541-09-3
Uranium nitride EC / List no: - | CAS no: 12058-37-6
[oxalato(2-)-O,O']dioxouranium EC / List no: 217-986-5 | CAS no: 2031-89-2
Triuranium octaoxide EC / List no: 215-702-4 | CAS no: 1344-59-8
-
-
Acute Tox. 2; STOT RE 2
urethane (INN); ethyl carbamate
200-123-1
51-79-6
Carc. 1B
UVCB condensation product of: tetrakis-hydroxymethylphosphonium chloride, urea and distilled hydrogenated C16-18 tallow alkylamine
ITC 826 CONCENTRATE
422-720-8
166242-53-1
Carc. 2; Acute Tox. 4; STOT RE 2; Skin Corr. 1B; Skin Sens. 1
Vaccinia virus
-
-
V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
valeric acid
203-677-2
109-52-4
Skin Corr. 1B
valinamide
D,L-VALINEAMIDE
402-840-7
20108-78-5
Repr. 2; Eye Irrit. 2; Skin Sens. 1
vamidothion (ISO); O,O-dimethyl S-2-(1-methylcarbamoylethylthio) ethyl phosphorothioate
218-894-8
2275-23-2
Acute Tox. 3; Acute Tox. 4
vanadium(IV) oxide hydrogen phosphate hemihydrate, lithium, zinc, molybdenum, iron and chlorine-doped
424-390-0
93280-40-1
Acute Tox. 4; STOT RE 2; Eye Dam. 1
vanadyl pyrophosphate
BTN; VPO CATALYST
406-260-5
58834-75-6
Eye Irrit. 2; Skin Sens. 1
Variant Creutzfeldt-Jakob disease
-
-
V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Variola (major and minor) virus
-
-
V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Venezuelan equine encephalomyelitis
-
-
V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
vernolate (ISO); S-propyl dipropylthiocarbamate
217-681-7
1929-77-7
Acute Tox. 4
Vesicular stomatitis virus
-
-
V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Vibrio cholerae (including El Tor)
-
-
B Bacteria and similar species
Vibrio parahaemolyticus
-
-
B Bacteria and similar species
Vibrio spp.
-
-
B Bacteria and similar species
vinclozolin (ISO); N-3,5-dichlorophenyl-5-methyl-5-vinyl-1,3-oxazolidine-2,4-dione
256-599-6
50471-44-8
Carc. 2; Repr. 1B; Skin Sens. 1
vinyl acetate
203-545-4
108-05-4
Flam. Liq. 2; Carc. 2; Acute Tox. 4; STOT SE 3
vinyl chloride; chloroethylene
200-831-0
75-01-4
Press. Gas; Flam. Gas 1; Carc. 1A
warfarin (ISO); 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one;
201-377-6
81-81-2
Repr. 1A; Acute Tox. 1; Acute Tox. 2; STOT RE 1
Waste solids, coal-tar pitch coking; Coal Tar Solids Residue [The combination of wastes formed by the coking of bituminous coal tar pitch. It consists predominantly of carbon.]
The combination of wastes formed by the coking of bituminous coal tar pitch. It consists predominantly of carbon.
295-549-8
92062-34-5
Carc. 1B
Wesselsbron virus
-
-
V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
West Nile fever virus
-
-
V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Western equine encephalomyelitis
-
-
V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
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