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4,4'-methylenediphenyl diisocyanate

EC / List no.: 202-966-0

CAS no.: 101-68-8

Mol. formula: C15H10N2O2

formula
GHS08: Serious Health Hazard GHS07: Health hazard

Danger! According to the harmonised classification and labelling (ATP01) approved by the European Union, this substance causes serious eye irritation, is harmful if inhaled, is suspected of causing cancer, may cause damage to organs through prolonged or repeated exposure, causes skin irritation, may cause an allergic skin reaction, may cause allergy or asthma symptoms or breathing difficulties if inhaled and may cause respiratory irritation.

  • C

Possibly Carcinogenic

  • Ss

Skin sensitising

  • Sr

Respiratory sensitising

This substance is manufactured and/or imported in the European Economic Area in 100 000 - 1 000 000 tonnes per year.

This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Consumer Uses

This substance is used in the following products: adhesives and sealants, coating products and polymers.
Other release to the environment of this substance is likely to occur from: indoor use and outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).

Article service life

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

Widespread uses by professional workers

This substance is used in the following products: adhesives and sealants and coating products.
This substance is used in the following areas: building & construction work, health services and printing and recorded media reproduction.
This substance is used for the manufacture of: machinery and vehicles.
Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Formulation or re-packing

This substance is used in the following products: coating products, inks and toners, polymers and cosmetics and personal care products.
Release to the environment of this substance can occur from industrial use: formulation of mixtures, formulation in materials, for thermoplastic manufacture and in the production of articles.

Uses at industrial sites

This substance is used in the following products: adhesives and sealants and coating products.
This substance is used in the following areas: formulation of mixtures and/or re-packaging.
This substance is used for the manufacture of: chemicals.
Release to the environment of this substance can occur from industrial use: for thermoplastic manufacture, in the production of articles, in processing aids at industrial sites, formulation of mixtures, formulation in materials and as an intermediate step in further manufacturing of another substance (use of intermediates).

Manufacture

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, formulation of mixtures and for thermoplastic manufacture.

The InfoCard summarises the non-confidential data on substances as held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The InfoCard is automatically generated. Information requirements under different legislative frameworks may therefore not be up–to–date or complete. Substance manufacturers and importers are responsible for consulting official publications. This InfoCard is covered by the ECHA Legal Disclaimer.

ECHA logo about INFOCARD - Last updated: 08/10/2019

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