Registration Dossier
Registration Dossier
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EC number: 948-068-9 | CAS number: -
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Title:
- Alkyl esters as skin permeation enhancers for indomethacin
- Author:
- Catz P, Friend DR
- Year:
- 1 989
- Bibliographic source:
- Int J Pharma, 55, 17-23
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- GLP compliance:
- not specified
- Type of method:
- flask method
Test material
- Reference substance name:
- Ethanol
- EC Number:
- 200-578-6
- EC Name:
- Ethanol
- Cas Number:
- 64-17-5
- Molecular formula:
- C2H6O
- IUPAC Name:
- ethanol
Constituent 1
- Specific details on test material used for the study:
- Described as 'reagent grade'. Used without further purification
Results and discussion
Partition coefficient
- Key result
- Type:
- log Pow
- Partition coefficient:
- 0.35
- Temp.:
- 24 °C
- pH:
- 7.4
Applicant's summary and conclusion
- Conclusions:
- The logKow for ethanol is -0.35
- Executive summary:
The logKow for ethanol is -0.35
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