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EC number: 609-496-9 | CAS number: 379685-94-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Oxidising properties
Administrative data
- Endpoint:
- oxidising solids
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.17 (Oxidising Properties (Solids))
- Version / remarks:
- -
- Deviations:
- no
- GLP compliance:
- no
Test material
- Reference substance name:
- Glycine, N-acetyl-N-[3-(trifluoromethyl)phenyl]valyl-, ethyl ester
- EC Number:
- 609-496-9
- Cas Number:
- 379685-94-6
- Molecular formula:
- C18H23F3N2O4
- IUPAC Name:
- Glycine, N-acetyl-N-[3-(trifluoromethyl)phenyl]valyl-, ethyl ester
- Test material form:
- solid: particulate/powder
- Remarks:
- Off white to beige powder with agglomerates
Constituent 1
- Specific details on test material used for the study:
- - Analytical purity: 98.5% (HPLC)- Lot/batch No.: 0161045- Expiration date of the lot/batch: 2018/06/16
Study design
- Contact with:
- powdered cellulose
Results and discussion
Test results (Oxidising solids)open allclose all
- Key result
- Sample tested:
- reference: 3:2 mixture potassium bromate + cellulose
- Parameter:
- burning rate
- Result:
- ca. 3.25 mm/s
- Remarks on result:
- other: mixture showing the highest burning rate
- Key result
- Sample tested:
- test mixture as specified
- Remarks:
- 10% test substance
- Parameter:
- burning rate
- Result:
- ca. 2.83 mm/s
- Remarks on result:
- other: mixture showing the highest burning rate
Any other information on results incl. tables
Observations
All reference substance mixtures showed clear signs of oxidising properties (cracks, sparkling).
All test substance mixtures burned with orange flame and carbonized.
Burning Rates Reference Substance
In the following table, the measured data of the reference substance are presented.
Burning Rate of Reference Substance Mixtures
% Ba(NO3)2 | Burning Time (s) | Burning Rate (mm/s) |
50 | 66.03 | 3.03 |
60 | 61.47 | 3.25 |
70 | 75.32 | 2.66 |
Burning Rates Test Substance
In the following table, the measured data of the test substance mixtures are presented.
Burning Rate of Test substance Mixtures
% Test Substance | Burning Time (s) | Burning Rate (mm/s) |
10 | 70.72 | 2.83 |
20 | 79.13 | 2.53 |
30 | 87.59 | 2.28 |
40 | 93.9 | 2.13 |
50 | 107.28 | 1.86 |
60 | 127.49 | 1.57 |
70 | 152.06 | 1.32 |
80 | 241.79 | 0.83 |
90 | 539.66 | 0.37 |
The mixture with 10 % test substanceMEXORYL SAR/20 shows the highest burning rate.
As the burning rate was lower than the highest burning rate of the reference substance mixtures, the determination of burning rate was repeated five times for each of the three mixtures test substance/cellulose with the highest burning rates.
The data are presented in the following tables.
Determination of burning rate mixture10/90% test substance / cellulose
Measurement | Burning Time (s) | Burning Rate (mm/s) |
1 | 71.42 | 2.80 |
2 | 69.89 | 2.86 |
3 | 70.77 | 2.83 |
4 | 71.12 | 2.81 |
5 | 69.49 | 2.88 |
6(from first performance) | 70.72 | 2.83 |
Mean |
| 2.83 |
Standard Deviation in mm/s |
| 0.03 |
Standard Deviation in % |
| 1.05 |
Determination of burning rate mixture20/80% test substance / cellulose
Measurement | Burning Time (s) | Burning Rate (mm/s) |
1 | 80.44 | 2.49 |
2 | 82.08 | 2.44 |
3 | 79.08 | 2.53 |
4 | 78.64 | 2.54 |
5 | 81.73 | 2.45 |
6(from first performance) | 79.13 | 2.53 |
Mean |
| 2.49 |
Standard Deviation in mm/s |
| 0.05 |
Standard Deviation in % |
| 1.82 |
Determination of burning rate mixture30/70% test substance / cellulose
Measurement | Burning Time (s) | Burning Rate (mm/s) |
1 | 93.49 | 2.14 |
2 | 86.58 | 2.31 |
3 | 89.01 | 2.25 |
4 | 90.04 | 2.22 |
5 | 91.98 | 2.17 |
6(from first performance) | 87.59 | 2.28 |
Mean |
| 2.23 |
Standard Deviation in mm/s |
| 0.06 |
Standard Deviation in % |
| 2.90 |
Result
The highest burning rate of the three mixtures test substance/cellulose with the highest burning rate was determined to be 2.83±0.03 mm/s. The maximum burning rate of the reference substance was determined to be 3.25 mm/s. Therefore, the test substance is considered to have no oxidising properties.
Validity
The single determinations of the burning rate may not differ more than 10% from the respective arithmetic mean. The following deviations were calculated:
Deviations from the Mean
Mixture | Mean Burning Rate | Difference in % of Replicates | |||||
% test substance / % cellulose | in mm/s | 1 | 2 | 3 | 4 | 5 | 6 |
10/90 | 2.83 | 1.2 | -1.0 | 0.3 | 0.8 | -1.5 | 0.2 |
20/80 | 2.49 | 0.3 | 2.3 | -1.4 | -1.9 | 1.9 | -1.3 |
30/70 | 2.23 | 4.0 | -3.6 | -0.8 | 0.4 | 2.5 | -2.4 |
None of the deviations surpasses 10%. Therefore, the study is considered as valid.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The highest burning rate of the three mixtures test substance/cellulose with the highest burning rate was determined to be 2.83 +/- 0.03 mm/s. The maximum burning rate of the reference substance was determined to be 3.25 mm/s. Therefore, the test substance is considered to have no oxidising properties.
- Executive summary:
The oxidising properties of the test item (solid) was performed with a not-GLP compliant study, according to the EU method A.17. The highest burning rate of the three mixtures test substance/cellulose with the highest burning rate was determined to be 2.83 +/- 0.03 mm/s. The maximum burning rate of the reference substance was determined to be 3.25 mm/s. Therefore, the test substance is considered to have no oxidising properties.
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