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Diss Factsheets
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EC number: 267-029-0 | CAS number: 67762-64-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The substance is a liquid at ambient temperature. It is highly insoluble in water (3.44 x 10-4g/L), has a low volatility (vapour pressure = 1.8x 10-5Pa at 25 °C) and has a high affinity for soil / sediment (log Koc in the range 5.14 to greater than 5.63). As such, any environmental release will result in most of the substance compartmentalising into the soil and sediment compartment, with little release directly to atmosphere.
An EPIWIN estimation have been undertaken on the most abundant structures present in the substance. The following partitioning data have been derived based on the EPIWIN Fugacity III model (Mackay et al. 1996):
- Air 0.0629 to 0.691%
- Water 13.3 to 19.9%
- Sediment 9.45 to 21.6%
- Soil 65 to 71.6%
Based on the model available, the substance will have a tendency to bind tightly primarily to soil and is likely to persist in the soil rather than distribute to soil pore water.
Based on the results of two studies, the read-across substance, decanoic acid, ester with 2-ethyl-2-(hydroxymethyl) -1,3-propanediol octanoate, is considered to be readily biodegradable. In the key study conducted according to OECD Guideline 301B, the biodegradation of the read-across substance was 72% after 28 days. In the supporting study conducted according to OECD Guideline 301B (with restrictions), the biodegradation was 79% after 29 days and 78% after 10 days. Therefore, by read-across, heptanoic acid, ester with 2-ethyl-2-(hydroxymethyl) -1,3-propanediol pentanoate is considered to be readily biodegradable.
On the basis of a weight of evidence approach using QSAR models, there is sufficient information available to state that the substance is not bioaccumulative in aquatic species. Whilst it is not possible to provide a definitive BCF value for the substance, the result is not above the threshold value quoted in the Regulation of 2000 or 5000 which indicates the potential to bioaccumulate. Therefore, the substance is not considered to be “bioaccumulative” or “very bioaccumulative” on the basis of the available data.
Finally, by read-across, the substance demonstrates low acute toxicity in mammalian studies. The substance is also not expected to bioaccumulate in the event of exposure of higher level organisms via ingestion of environmental organisms, therefore effects due to secondary poisoning can be excluded.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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