Gadolinium trinitrate

Short-term toxicity to fish

Administrative data

Endpoint:

short-term toxicity to fish

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

1995

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

secondary literature

Remarks:

original source not available

Data source

Reference

Reference 1

Reference Type:

other: student thesis

Title:

Aquatisch ecotoxicologisch onderzoek van zeldzame aardmetalen.

Author:

Den Ouden ACPH

Year:

1995

Bibliographic source:

Student Report HLO Delft, under the supervision of Hooftman RN, TNO-MW, Delft

Reference 2

Reference Type:

review article or handbook

Title:

Maximum permissible concentrations and negligible concentrations for Rare Earth elements (REEs)

Author:

Sneller FEC, Kalf DF, Weltje L, Van Wezel AP

Year:

2000

Bibliographic source:

RIVM (Rijksinstituut voor Volksgezondheid en Milieu) Bilthoven, The Netherlands; report 601501 011

Materials and methods

Test guideline

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 203 (Fish, Acute Toxicity Test)

GLP compliance:

not specified

Test material

Test material information

Details on test material:

No details on test material reported in Sneller et al. (2000).

Sampling and analysis

Analytical monitoring:

yes

Details on sampling:

no details available in Sneller et al. (2000)

Test solutions

Vehicle:

no

Details on test solutions:

no details reported in Sneller et al. (2000)

Test organisms

Test organisms (species):

other: Brachydanio rerio

Details on test organisms:

Brachydanio rerio
No further details reported in Sneller et al. (2000).

Study design

Test type:

semi-static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

96 h

Test conditions

Hardness:

210 mg CaCO3/L

pH:

6.5-8.0

Nominal and measured concentrations:

Measured

Details on test conditions:

Test performed in standard test medium (not specified).

Results and discussion

Effect concentrations

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

19 mg/L

Nominal / measured:

meas. (not specified)

Conc. based on:

element

Basis for effect:

mortality (fish)

Remarks on result:

other: not clear if dissolved or total Gd was measured

Applicant's summary and conclusion

Conclusions:

The 96-h LC50 of gadolinium for Brachydanio rerio was determined to be 19 mg Gd/L (based on measured concentrations, however not clear if dissolved or total Gd was measured). This study was not included in the weight of evidence approach since the original source is not available and more specifically because the secondary source does not mention information on the identity of the test material (an unspecified gadolinium salt was used).