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EC number: 220-877-5 | CAS number: 2923-16-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 18 jan 2000 to 20 jan 2000
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- no
- Details on test solutions:
- The stock solution was prepared by dissolving the test substance directly in the test medium at a concentration of 100 mg/kg (100 mg/L).
Tests solutions were prepared by dilution of the stock solution to obtain the appropriate test concentrations as follow: 0.1, 0.35, 1, 3.5, 10, 35 and 100 mg/L. - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Daphnia magna
- Strain: Strauss 1820
- Source: Laboratory CRIT-D, Décines
No more data - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Test temperature:
- 18 - 22°C (variability: +/- 1°C)
- Nominal and measured concentrations:
- 0, 0.1, 0.35, 1, 3.5, 10, 35 and 100 mg/L (nominal).
- Details on test conditions:
- TEST SYSTEM
- Test vessel: 100 mL beaker
- Type (delete if not applicable): open
- Aeration: no data
- No. of organisms per vessel: 20
- No. of vessels per concentration (replicates): 1 except for the 100 mg/L dose, in duplicate
- No. of vessels per control (replicates): 1
TEST MEDIUM / WATER PARAMETERS
- CaCl2, 2H2O: 0.294 g
- MgSO4, 7H2O: 0.12325 g
- NaHCO3: 0.06475 g
- KCl: 0.00575 g
- Bidistilled water: up to 1000 mL
OTHER TEST CONDITIONS
- Adjustment of pH: no data
- Photoperiod: none, darkness
- Light intensity: darkness
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : mortality, immobilization.
TEST CONCENTRATIONS
- Spacing factor for test concentrations: 2.8 or 3.5
- Test concentrations: 0, 0.1, 0.35, 1, 3.5, 10, 35 and 100 mg/L - Reference substance (positive control):
- yes
- Remarks:
- Potassium dichromate
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Details on results:
- No mortality has been observed during the study.
- Results with reference substance (positive control):
- - Results with reference substance valid: yes
- EC50 (24h): 0.91 mg/L (CL: 0.76 - 1.2 mg/L) - Reported statistics and error estimates:
- Probit method for reference substance.
- Validity criteria fulfilled:
- yes
- Remarks:
- <10% f mortality in controls was fulfilled; Oxygen demand >= 3mg/L: no data
- Conclusions:
- Potassium trifluoroacetate is not harmful to daphnia
- Executive summary:
In this key study, Daphnia magna were exposed to Potassium trifluoroacetate at doses from 0 to 100 mg/L, following the EC C2 guideline. There was no mortality observed during the study. The 48-hour EC50 was higher than 100 mg/L. In these conditions, Potassium trifluoroacetate is not harmful to daphnia based on CLP 1272/2008 criteria.
Reference
Description of key information
No effect of TFAK was observed to Daphnia magna at 100 mg/L.
Key value for chemical safety assessment
Additional information
A reliable key study is available for this endpoint. In this key study, Daphnia magna were exposed to Potassium trifluoroacetate at doses from 0 to 100 mg/L, following the EC C2 guideline. There was no mortality observed during the study. The 48-hour EC50 was higher than 100 mg/L. Under these conditions, Potassium trifluoroacetate is not harmful to daphnia based on EU criteria (CLP 1272/2008).
Moreover, a reliable key study is available for sodium trifluoroacetate which is used in a read-across approach. In this supporting study, the acute toxicity of sodium trifluoroacetate to water fleas Daphnia magna (0-24 hours old) was studied in a limit test according OECD Guideline 202 (OECD, 1984) at nominal test concentrations of 0 and 1200 mg/l in ISO-water. Samples of the test solutions were taken 0 and 48 hours after test initiation and analysed by ion chromatography. The concentration of sodium trifluoroacetate remained constant during the test. No immobilization was observed during the test in any test concentration and no other effects were observed. Therefore, based on the nominal test concentrations, for sodium trifluoroacetate, the EC50 (48h) is > 1200 mg/L.
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