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EC number: 210-695-4 | CAS number: 621-62-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: OECD Guideline Study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 991
- Report date:
- 1991
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- GLP compliance:
- yes
Test material
- Reference substance name:
- Ethane, 2-Chloro-1, 1-Dimethoxy-
- IUPAC Name:
- Ethane, 2-Chloro-1, 1-Dimethoxy-
- Reference substance name:
- 97-97-02
- IUPAC Name:
- 97-97-02
- Reference substance name:
- 2-chloro-1,1-dimethoxyethane
- EC Number:
- 202-624-0
- EC Name:
- 2-chloro-1,1-dimethoxyethane
- Cas Number:
- 97-97-2
- Molecular formula:
- C4H9ClO2
- IUPAC Name:
- 2-chloro-1,1-dimethoxyethane
- Test material form:
- other: liquid
- Details on test material:
- - Name of test material (as cited in study report): Chloroacetaldehyde dimethylacetal
- Physical state: colourless liquid
- Analytical purity: 98%
Constituent 1
Constituent 2
Constituent 3
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
- Water solubility: 52.0 g/L at 20°C
- vapor pressure: 9 hPA at 20°C; 50 hPa at 50°C
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- not specified
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method: stock solution of 0.5 g/L and 0.2 g/L
test concentration (max. 100mL) and 6.4mL synthetic sewage with tab water are filled up to a volume of 120mL in 200mL flasks. The end volume of 200mL is reached after adding 80mL inoculum.
- Controls: 3,5-Dichlorophenol (pH 7-8)
Test organisms
- Test organisms (species):
- activated sludge
- Details on inoculum:
- - Preparation of inoculum for exposure: set down of sludge to separate rough sludge parts. The rest of the sludge is filled up with tab water in a 2L PE-bottle. The procedure will be repeated 3 times.
- Pretreatment: aeration at 20 +/- 2 °C. pH proved and if necessary adjusted to 6-8
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 30 min
Test conditions
- Hardness:
- no data
- Test temperature:
- 20 +/- 2°C
- pH:
- 6-7
- Dissolved oxygen:
- oxygen depletion in mg O2/L * h:
stock 1: 38.0
stock 2: 64.5 - Salinity:
- no data
- Nominal and measured concentrations:
- 12.5, 25, 37.5, 50, 100 mg/L
- Details on test conditions:
- TEST SYSTEM
- Test vessel: flask
- Aeration: yes
TEST MEDIUM / WATER PARAMETERS
- synthetic sewage g/L: 16.0g Pepton; 11.0g meat extract; 3.0g urea; 0.7g NaCl; 0.4g CaCl2 - 2 H2O; 0.2g MgSO4 - 7 H2O; 2.8g K2HPO4 - Reference substance (positive control):
- yes
- Remarks:
- 3.5 Dichlorophenol
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 30 min
- Dose descriptor:
- EC50
- Effect conc.:
- 22.9 other: mg O2/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- other: reference substance
- Duration:
- 30 min
- Dose descriptor:
- EC50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Details on results:
- Chloroacetaldehyde dimethylacetal was tested in an activated sludge respiration inhibition test according to OECD guideline 209. At the used concentrations no inhibition of the oxygen depletion microorganisms was shown. Consequently no EC20-, EC50- and EC80 value can be recorded.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- Chloroacetaldehyde dimethylacetal was tested in an activated sludge respiration inhibition test according to OECD guideline 209. At the used concentrations no inhibition of the oxygen depletion microorganisms was shown. Consequently no EC20-, EC50- and EC80 value can be recorded.
- Executive summary:
Chloroacetaldehyde dimethylacetal was tested in an activated sludge respiration inhibition test according to OECD guideline 209. At the used concentrations no inhibition of the oxygen depletion microorganisms was shown. Consequently no EC20-, EC50- and EC80 value can be recorded.
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