EU-MEDICAL_DEVICES_REGULATION-ANX_I_SEC_10

Medical Devices Regulation - Hazardous Substances

EU. Hazardous Substances for Purposes of Medical Devices Regulation 2017/745/EU, 5 May 2017, as amended by Regulation 2020/561/EU, 24 April 2020

This list contains hazardous substances for purposes of the Medical Devices Regulation (MDR), based on the legislation's Annex I general safety and performance requirements, including for chemical, physical and biological properties. Specifically, the non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list).

Last updated 23 April 2024. Database contains 4917 unique substances/entries.

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Showing 1 - 50 of 4,917 results.

Substance Name	EC No.	CAS No.	EU CLP (1272/2008)	EU REACH: List of SVHC	EU_BA Directive 2000/54/EC
ε-caprolactam	203-313-2	105-60-2	Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2			Details
α[2-[[[(2-hydroxyethyl)methylamino]acetyl]amino]propyl]-ω nonylphenoxy)poly[oxo(methyl-1,2-ethanediyl)] PC-709	413-420-8	144736-29-8	Skin Corr. 1B; Skin Sens. 1			Details
α-hydroxypoly(methyl-(3-(2,2,6,6-tetramethylpiperidin-4-yloxy)propyl)siloxane)	639-478-6	182635-99-0	Acute Tox. 4; Skin Corr. 1B			Details
α-cypermethrin (ISO); racemate comprising (R)-α-cyano-3-phenoxybenzyl (1S,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate; (S)-α-cyano-3-phenoxybenzyl(1R, 3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	614-054-3	67375-30-8	Acute Tox. 3; STOT RE 2; STOT SE 3			Details
α-chlorotoluene; benzyl chloride	202-853-6	100-44-7	Carc. 1B; Acute Tox. 3; Acute Tox. 4; STOT RE 2; STOT SE 3; Skin Irrit. 2; Eye Dam. 1			Details
α-bromotoluene; benzyl bromide	202-847-3	100-39-0	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2			Details
α-[3-(1-oxoprop-2-enyl)l-1-oxypropyl]dimethoxysilyloxy-ω-[3(1-oxoprop-2-enyl)-1-oxypropyl]dimethoxysilyl poly(dimethylsiloxane) ACRYLOXYPROPYL DIMETHOXYSILOXY TERMINATED POLYDIMETHYL SILOXANE	415-290-8	193159-06-7	Skin Sens. 1			Details
α,α-Bis[4-(dimethylamino)phenyl]-4 (phenylamino)naphthalene-1-methanol; C.I. Solvent Blue 4	229-851-8	6786-83-0		C Carcinogenic (article 57a)		Details
α, α-dimethylbenzyl hydroperoxide; cumene hydroperoxide	201-254-7	80-15-9	Org. Perox. E; Acute Tox. 3; Acute Tox. 4; STOT RE 2; Skin Corr. 1B			Details
α, α-dichlorotoluene; benzylidene chloride; benzal chloride	202-709-2	98-87-3	Carc. 2; Acute Tox. 3; Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Eye Dam. 1			Details
α, α, α-trifluorotoluene; benzotrifluoride	202-635-0	98-08-8	Flam. Liq. 2			Details
α, α, α-trichlorotoluene; benzotrichloride	202-634-5	98-07-7	Carc. 1B; Acute Tox. 3; Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Eye Dam. 1			Details
α, α, α,4-tetrachlorotoluene; p-chlorobenzotrichloride	226-009-1	5216-25-1	Carc. 1B; Repr. 2; STOT RE 1; Acute Tox. 4; STOT SE 3; Skin Irrit. 2			Details
zoxamide (ISO); (RS)-3,5-dichloro-N-(3-chloro-1-ethyl-1-methyl-2-oxopropyl)-p-toluamide	605-037-1	156052-68-5	Skin Sens. 1			Details
zirconium powder (pyrophoric);zirconium powder, dry (non pyrophoric)	231-176-9	7440-67-7	Water-react. 1; Pyr. Sol. 1			Details
zirconium powder (pyrophoric);zirconium powder, dry (non pyrophoric)	231-176-9	7440-67-7	Self-heat. 1			Details
Zirconia Aluminosilicate Refractory Ceramic Fibres	936-037-2	-		C Carcinogenic (article 57a)		Details
ziram (ISO); zinc bis dimethyldithiocarbamate	205-288-3	137-30-4	Acute Tox. 2; Acute Tox. 4; STOT RE 2; STOT SE 3; Eye Dam. 1; Skin Sens. 1			Details
zineb (ISO); zinc ethylenebis(dithiocarbamate) (polymeric)	235-180-1	12122-67-7	STOT SE 3; Skin Sens. 1			Details
zinc-bis(4-(n-octyloxycarbonylamino)salicylate) dihydrate	417-130-2	1379689-21-0	Eye Dam. 1			Details
zinc sulphate (hydrous) (mono-, hexa-and hepta hydrate)	616-096-8	7446-19-7	Acute Tox. 4; Eye Dam. 1			Details
zinc sulphate (anhydrous)	231-793-3	7733-02-0	Acute Tox. 4; Eye Dam. 1			Details
zinc powder — zinc dust (pyrophoric)	231-175-3	7440-66-6	Water-react. 1; Pyr. Sol. 1			Details
zinc hexacyanocobaltate(III), tertiary butyl alcohol/polypropylene glycol complex	425-240-7	-	Eye Dam. 1			Details
zinc chromates including zinc potassium chromate show/hide Pentazinc chromate octahydroxide EC / List no: 256-418-0 \| CAS no: 49663-84-5 C.I. Pigment Yellow 36 EC / List no: 609-398-6 \| CAS no: 37300-23-5 Zinc chromate EC / List no: 236-878-9 \| CAS no: 13530-65-9 Potassium hydroxyoctaoxodizincatedichromate(1-) EC / List no: 234-329-8 \| CAS no: 11103-86-9 Chromic acid, potassium zinc salt EC / List no: 255-252-6 \| CAS no: 41189-36-0 Zinc dichromate EC / List no: 237-843-0 \| CAS no: 14018-95-2	-	-	Carc. 1A; Acute Tox. 4; Skin Sens. 1			Details
zinc chloride	231-592-0	7646-85-7	Acute Tox. 4; Skin Corr. 1B			Details
zinc bis(diethyldithiocarbamate)	238-270-9	14324-55-1	Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1			Details
zinc bis(dibutyldithiocarbamate)	205-232-8	136-23-2	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1			Details
zinc 2-hydroxy-5-C13-18 alkylbenzoate Z-6	402-280-3	149144-82-1	Eye Irrit. 2; Skin Irrit. 2			Details
Yersinia spp.	-	-			B Bacteria and similar species	Details
Yersinia pseudotuberculosis	-	-			B Bacteria and similar species	Details
Yersinia pestis	-	-			B Bacteria and similar species	Details
Yersinia enterocolitica	-	-			B Bacteria and similar species	Details
Yellow fever	-	-			V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.	Details
Yatapox virus	-	-			V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.	Details
xylylcarb (ISO); 3,4-dimethylphenyl N-methylcarbamate; 3,4-xylyl methylcarbamate; MPMC	219-364-9	2425-10-7	Acute Tox. 4			Details
xylidines with the exception of those specified elsewhere in this Annex; dimethyl anilines with the exception of those specified elsewhere in this Annex	215-091-4	1300-73-8	Acute Tox. 3; STOT RE 2			Details
xylenol	215-089-3	1300-71-6	Acute Tox. 3; Skin Corr. 1B			Details
xylene	215-535-7	1330-20-7	Flam. Liq. 3; Acute Tox. 4; Skin Irrit. 2			Details
XMC; 3,5-xylyl methylcarbamate	607-955-8	2655-14-3	Acute Tox. 4			Details
Wuchereria bancrofti	-	-			P Parasites	Details
Whitepox virus	-	-			V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.	Details
white phosphorus	601-810-2	12185-10-3	Pyr. Sol. 1; Acute Tox. 2; Skin Corr. 1A			Details
Western equine encephalomyelitis	-	-			V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.	Details
West Nile fever virus	-	-			V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.	Details
Wesselsbron virus	-	-			V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.	Details
Waste solids, coal-tar pitch coking; Coal Tar Solids Residue [The combination of wastes formed by the coking of bituminous coal tar pitch. It consists predominantly of carbon.] The combination of wastes formed by the coking of bituminous coal tar pitch. It consists predominantly of carbon.	295-549-8	92062-34-5	Carc. 1B			Details
warfarin (ISO); 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one;	201-377-6	81-81-2	Repr. 1A; Acute Tox. 1; Acute Tox. 2; STOT RE 1			Details
vinyl chloride; chloroethylene	200-831-0	75-01-4	Press. Gas; Flam. Gas 1; Carc. 1A			Details
vinyl acetate	203-545-4	108-05-4	Flam. Liq. 2; Carc. 2; Acute Tox. 4; STOT SE 3			Details

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EU-MEDICAL_DEVICES_REGULATION-ANX_I_SEC_10

EU-MEDICAL_DEVICES_REGULATION-ANX_I_SEC_10

Medical Devices Regulation - Hazardous Substances

EU. Hazardous Substances for Purposes of Medical Devices Regulation 2017/745/EU, 5 May 2017, as amended by Regulation 2020/561/EU, 24 April 2020

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Last updated 23 April 2024. Database contains 4917 unique substances/entries.

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