Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 411-030-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Guidance on Safe Use
Administrative data
First-aid measures
Emergency measure - Inhalation: Dust content found to be very low but if inhaled, move to
fresh air. Seek medical advice if exposure severe or if
signs of discomfort noted.
Emergency measure - Eyes: Irrigate with saline water and seek medical advice if
syptoms of irritation are noted.
Emergency measure - Skin: Wash with water and seek medical advice if symptoms of
irritation are noted.
Emergency measure - Ingestion: Drink water or milk. Material will quickly hydrolyse in the
stomach to Ioversol and studies conducted indicate a very
low rate of adsorbance through the stomach. Seek medical
advice if discomfort is noted.
Fire-fighting measures
Recommended extinguishing agent: Water, foam, carbon dioxide. No special recommendations
Product arising from burning: Oxides of carbon and nitrogen as well as iodine products and
elemental iodine.
Product determined by test: N
Protective equipment: Breathing apparatus, face shields and gloves in addition to
normal precautions.
Accidental release measures
Emergency measures in case of spillage: Sweep up and dispose of as chemical waste. Precautions
advised against inhalation of dust if dry. Rinse area with
water but avoid entry to water courses untreated.
Handling and storage
Handling: Material is solid and although respirable fraction is very
low, dust masks conforming to EN 149 FF P1 should be worn
when handling material. It is considered to be good working
practice to wear gloves and goggles corresponding to BS 2093
when handling the material or preparations.
Storage: No special storage conditions but the material should be
kept dry. Cool, dark and dry conditions are recommended.
Transport information
Shippingopen allclose all
SpecialProvisionsopen allclose all
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
Shippingopen allclose all
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
Shippingopen allclose all
Special provisions / remarks
- Remarks:
- Transport: No special precautions. Keep dry.
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Stability and reactivity
Danger other than fire: No other danger perceived when used and handled in
accordance with recommendations
Chemical reaction with water: Reacts with water slowly in the pH range of 4-7 and rapidly
at pH values outside this range. The final reaction product
is Ioversol which is more stable and inert than MP-633.
Ioversol is marketed as an X ray imaging aid.
Disposal considerations
Industry - Possibility of recovery/recycling: It is not considered appropriate to recover or recycle lost
material. The production process in which MP-633 is used
relies on a complete conversion of MP-633 to final product,
Ioversol.
Industry - Possibility of neutralisation: Material can be converted with acids or bases to a more
inert product, Ioversol.
Industry - Possibility of destruction: controlled discharge: Not planned for MP-633. Effects on sewage treatment works
could be possible due to a release of Iodine compounds
during degradation of the product. Direct effects on the
environment are considered to be minimal.
Industry - Possibility of destruction - incineration: (633) Incinerate high temperature - long burn (*) with flue
gas scrubbing.
Recommended for disposal. Iodine products may be formed.
(*) Minimum temperature of 1200°C, at least 2 seconds
residence time, excess oxygen.
Industry - Possibility of destruction - water purification: Production of Iodine products during degradation may affect
sewage treatment plants. Partly biodegradable.
Industry - Possibility of destruction - other: None.
Public at large - Possibility of recovery/recycling: Not applicable (see Section A.6.1.1)
Public at large - Possibility of neutralisation: Not applicable (see Section A.6.1.2)
Public at large - Possibility of destruction: controlled discharge: Not applicable (see Section A.6.1.3)
Public at large - Possibility of destruction - incineration: Not applicable (see Section A.6.1.3)
Public at large - Possibility of destruction - water purification: Not applicable (see Section A.6.1.3)
Public at large - Possibility of destruction - others: None.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.