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EC number: 700-891-2
CAS number: -
To estimate the potential for toxicity and lethality of a single dose
level of a test substance in the rat.
This tudy was conduced according to OECD 401 guideline in compliance
with Good Laboratory Practices.
The test item was administred to 10 albnino rat, Sprague Dawley OFA (5
males and 5 females) at the dose of 2000mg/kg body weight.
Animals have been fasted prior to substance administration by
withholding food overnight. They receive by gavage, according to the
bodyweight, the product diluted in distilled water (Meram batch 62417),
previously heated at 80°C, at the single dose of 2000mg/kg under a
constant volume of 10 mL/kg. The preparation is kept up under magnetic
stirring till obtaining a homogeneous mixture, to ambient temperature.
The test item does not cause any death.
The test item has no significant toxic effect on the animals' behaviour
or vegetative functions.
the test item does not modify their weight growth.
The test item does not cause any gross lesion visible at autopsy.
Under the experimental conditions adopted, oral LD0 of the test
preparation is higher than 2000 mg/kg in the rat.
According to directive 67/548/EEC and regulation EC 1272/2008, the test
preparation is unclassified if swallowed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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