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Diss Factsheets
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EC number: 211-623-4 | CAS number: 675-62-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term measured data for the registered substance dichloromethyl(3,3,3-trifluoropropyl)silane were available for fish, invertebrates and algae.
In an acute fish toxicity test according OECD 203 and GLP (Fournier, 2012), the 96h LC50for rainbow trout Oncorhynchus mykiss exposed to dichloromethyl(3,3,3-trifluoropropyl)silane was 35 mg/l in a static system, the NOEC was 25 mg/l. A 48-h EL50value of > 100 mg/l and a NOELR of 4.64 mg/l have been determined for the effects of the test substance on mobility of Daphnia magna (OECD 202, LPT 2003).
A 72 hour EC50value of > 10 mg/l and NOEC of 10 mg/l have been determined for the effects on growth rate of and biomass of Pseudokirchneriella subcapitata (OECD 201, Softcheck 2012).10 mg/l was the maximum achievable concentration in algal growth medium (the dilution water used for this study) that will yield a fully soluble test concentration without the formation of insoluble polymer structures.
Ecotoxicity data were predominantly generated on the parent compound, which was supposed to display the principal aquatic hazard, this chlorosilane will fully hydrolyse within one minute; the results of each of these studies are interpreted with reference to nominal concentrations of the test substance. However, the test organisms were exposed to the hydrolysis products of the substance. It can be concluded that the hydrolysis products shows no toxicity up to the highest tested concentrations in the studies and exposure to the possible degradation products did not induce additional effects on survival.
The influence of the test item dichloromethyl(3,3,3-trifluoropropyl)silane on bacteria was investigated according to standard guideline (ISO 10712) and GLP (Hanstveit 1999). No inhibition in growth of the Pseudomonas putida was recorded in the limit concentration of dichloromethyl(3,3,3-trifluoropropyl)silane tested. Hence, the 17 hour EC10was > 100 mg/l.
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