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EC number: 433-480-9
CAS number: 623-53-0
Table 1: Results of Comet Assay
Direct exposure of mammalian cells to dimethyl carbonate at a relatively
high concentration (150 mg/mL) caused no significant DNA damage,
visualised as comet cells. It is reasonable to predict that ethyl methyl
carbonate would give a similarly negative result in this assay: as its
predicted hepatic metabolites (ethanol, methanol, carbon dioxide) are
generally recognised as non-mutagenic, omission of cell exposure in the
presence of of a liver enzyme metabolising system is not considered to
invalidate a conclusion of non-genotoxicity.
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