Registration Dossier
Registration Dossier
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EC number: 236-740-8 | CAS number: 13472-08-7
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
No activated sludge respiration inhibition study with the test substance is available. An activated sludge respiration inhibition study with 2,2’-azobis(isobutyronitrile) was used to fulfill the data gap for the test substance.The underlying hypothesis for the read-across is based on the fact that the mode of action and chemical class specifics are relevant. Additional documentation, provided within the IUCLID Assessment Reports section, supports the read-across approach.
A static, 3-hour respiration inhibition study in domestic activated sludge with 2,2‘-azobis(isobutyronitrile) was performed. The 3-hour NOEC and EC50 in activated sludge were >1000 mg/L, based on respiration rate. Converted to 2,2'-azobis[2-methylbutyronitrile] this value is 1171 mg/L.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 171 mg/L
- EC10 or NOEC for microorganisms:
- 1 171 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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